Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2724247 | 0.81 | ALDH1A1 (0.33) | P2RX7ALDH1A1KDM4ERXFP1TDP1 | |
| SCHEMBL2723364 | 0.77 | TGM2 (0.45) | P2RX7ALDH1A1LMNAKMT2ATDP1 | |
| SCHEMBL202718 | 0.71 | MEN1 (0.61) | ALDH1A1KDM4ETP53CYP1A2CYP2C19 | |
| SCHEMBL731190 | 0.71 | KMT2A (0.50) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13450133 | 0.70 | P2RX7 (0.36) | P2RX7ALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL5024307 | 0.69 | SMN1; SMN2 (0.56) | ALDH1A1LMNAKDM4ETP53NPC1 | |
| SCHEMBL13085011 | 0.69 | ALDH1A1 (0.34) | P2RX7ALDH1A1LMNACYP3A4NPC1 | |
| SCHEMBL11985093 | 0.69 | ALDH1A1 (0.35) | P2RX7ALDH1A1LMNAKDM4ENPC1 | |
| SCHEMBL59797 | 0.68 | ALDH1A1 (0.47) | ALDH1A1LMNAKDM4ENPC1RAB9A | |
| SCHEMBL11234331 | 0.68 | TGFBR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4612392-A | N-substituted acrylamide and methacrylamide derivatives and their preparation | BASF AKTIENGESELLSCHAFT (DE) | 1986-09-16 | — | — | US | claimed |
| US-10023782-B2 | Salt-tolerant, thermally-stable rheology modifiers | ISP INVESTMENTS LLC (US) | 2018-07-17 | — | — | US | disclosed |
| US-20170335162-A1 | SALT-TOLERANT, THERMALLY-STABLE RHEOLOGY MODIFIERS | HERCULES LLC | 2017-11-23 | — | — | US | disclosed |
| US-9611416-B2 | Salt-tolerant, thermally-stable rheology modifiers | ISP INVESTMENTS LLC (US) | 2017-04-04 | — | — | US | disclosed |
| US-20130324443-A1 | SALT-TOLERANT, THERMALLY-STABLE RHEOLOGY MODIFIERS | ISP INVESTMENTS INC. (US) | 2013-12-05 | — | — | US | disclosed |
| WO-2013162902-A1 | SYNERGISTIC COMBINATION OF A FLUID LOSS ADDITIVE AND RHEOLOGY MODIFIER | ISP INVESTMENTS INC (US) | 2013-10-31 | — | — | WO | disclosed |
| WO-2013138156-A1 | SYNTHESIS AND APPLICATION OF HIGH PRESSURE HIGH TEMPERATURE FLUID LOSS ADDITIVE AND RHEOLOGY STABILIZER | ISP INVESTMENTS INC. (US) | 2013-09-19 | — | — | WO | disclosed |
| WO-2012061147-A1 | SALT-TOLERANT, THERMALLY-STABLE RHEOLOGY MODIFIERS | ISP INVESTMENTS INC. (US) | 2012-05-10 | — | — | WO | disclosed |
| US-4612392-A | N-substituted acrylamide and methacrylamide derivatives and their preparation | BASF AKTIENGESELLSCHAFT (DE) | 1986-09-16 | — | — | US | disclosed |