Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | SCN4A | P35499 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12172005 | 0.93 | LMNA (0.43) | LMNAMAOAPTGS1KCNA3SCN4A | |
| SCHEMBL13085598 | 0.85 | LMNA (0.37) | LMNAMAOAPTGS1KCNA3SCN4A | |
| SCHEMBL27438647 | 0.83 | LMNA (0.36) | LMNAMAOAPTGS1SCN4ACYP2D6 | |
| SCHEMBL7270606 | 0.83 | LMNA (0.50) | LMNAMAOAPTGS1KCNA3SCN4A | |
| SCHEMBL6627513 | 0.82 | LMNA (0.46) | LMNAMAOAPTGS1KCNA3SCN4A | |
| SCHEMBL26802641 | 0.81 | ALDH1A1 (0.40) | LMNAALDH1A1 | |
| SCHEMBL17034727 | 0.81 | CYP2C9 (0.55) | LMNAMAOAPTGS1KCNA3SCN4A | |
| SCHEMBL12978498 | 0.80 | LMNA (0.45) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL27251461 | 0.79 | PPARD (0.38) | LMNACYP2C9TSHRALDH1A1 | |
| SCHEMBL12978503 | 0.78 | PLA2G2A (0.51) | MAOAADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129553-A1 | RHEOLOGY MODIFIER FOR IMPROVED VISCOSITY LOSS ON TINTING IN PAINT FORMULATIONS CONTAINING ORGANO-PHOSPHORUS-FUNCNTIONALIZED LATEXES | ROHM AND HAAS COMPANY (US) | 2024-06-20 | — | — | WO | disclosed |