⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL144087 | 0.73 | DDAH1 (1.00) | — | |
| SCHEMBL191955 | 0.73 | MEN1 (1.00) | — | |
| SCHEMBL965041 | 0.71 | — | — | |
| SCHEMBL271954 | 0.71 | — | — | |
| SCHEMBL7772595 | 0.69 | — | — | |
| SCHEMBL23182834 | 0.69 | — | — | |
| SCHEMBL8522944 | 0.69 | — | — | |
| SCHEMBL4114252 | 0.69 | — | — | |
| SCHEMBL914712 | 0.69 | — | — | |
| SCHEMBL272575 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | claimed |
| US-5910609-A | HYDROXAMIC ACID COLLAGENASE INHIBITORS; PEPTIDE DERIVATIVES; ANTIINFLAMMATORY, ANTIARTHRITIC, ANTITUMOR AND WOUND HEALING AGENTS; BONE, SKIN, VISION DISORDERS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1999-06-08 | — | — | US | claimed |
| US-5494666-A | BETA-LACTAMASE INHIBITORS, ANTIBACTERIALS | HOFFMANN-LA ROCHE INC. (US) | 1996-02-27 | — | — | US | claimed |
| US-5464617-A | 1H-2,6a-diazacyclobut(cd)indene-6-carboxylic acid derivatives, antibiotics | HOFFMANN-LA ROCHE INC. (US) | 1995-11-07 | — | — | US | claimed |
| US-5453438-A | Hydroxamic acid based collagenase inhibitors | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-09-26 | — | — | US | claimed |
| US-5304604-A | Treating diseases involving tissue degradation, promoting wound healing | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-04-19 | — | — | US | claimed |
| EP-0175363-B1 | 4,5-DIHYDRO-3(2H)-PYRIDAZINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE | CASSELLA Aktiengesellschaft (DE) | 1990-01-17 | — | — | EP | claimed |
| US-4839352-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1989-06-13 | — | — | US | claimed |
| US-4816454-A | CARDIOVASCULAR DISORDERS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1989-03-28 | — | — | US | claimed |
| EP-0234516-A1 | 1,6-Naphthyridine derivatives, process for their preparation and medicine containing them for the treatment of vascular diseases | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1987-09-02 | — | — | EP | claimed |
| EP-0175363-A2 | 4,5-Dihydro-3(2H)-pyridazinones, process for their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1986-03-26 | — | — | EP | claimed |
| EP-0113245-A2 | Cephalosporin derivatives | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-07-11 | — | — | EP | claimed |
| US-4310459-A | Process for producing carbamoyl substituted penams and carbamoyl substituted cephams from penicillin sulfoxide esters | BRISTOL-MYERS COMPANY (US) | 1982-01-12 | — | — | US | claimed |
| US-20140243340-A1 | CYTOCHROME P450 OXIDASE INHIBITORS AND USES THEREOF | ABBVIE INC. (US) | 2014-08-28 | — | — | US | disclosed |
| US-8741938-B2 | Compounds that are useful for improving pharmacokinetics | ABBVIE INC. (US) | 2014-06-03 | — | — | US | disclosed |
| US-20130317071-A1 | NOVEL COMPOUNDS THAT ARE USEFUL FOR IMPROVING PHARMACOKINETICS | ABBVIE INC (US) | 2013-11-28 | — | — | US | disclosed |
| US-4035359-A | 6α, β-Substituted penicillin derivatives | MERCK & CO., INC. (US) | 1977-07-12 | — | — | US | disclosed |
| US-4032521-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1977-06-28 | — | — | US | disclosed |
| US-3974151-A | Cephalosporin compounds | MERCK & CO., INC. (US) | 1976-08-10 | — | — | US | disclosed |
| US-3947413-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1976-03-30 | — | — | US | disclosed |