⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL144087 | 0.76 | DDAH1 (1.00) | — | |
| SCHEMBL191955 | 0.76 | MEN1 (1.00) | — | |
| SCHEMBL272575 | 0.71 | — | — | |
| SCHEMBL4114252 | 0.71 | — | — | |
| SCHEMBL8522944 | 0.71 | — | — | |
| SCHEMBL23182834 | 0.71 | — | — | |
| SCHEMBL272574 | 0.71 | — | — | |
| SCHEMBL914712 | 0.71 | — | — | |
| SCHEMBL10872946 | 0.69 | — | — | |
| SCHEMBL14093836 | 0.69 | CYP1A2 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110142762-A1 | Conjugates for medical imaging comprising carrier, targeting moiety and a contrast agent | NOVOZYMES BIOPHARMA DK A/S (DK) | 2011-06-16 | — | — | US | claimed |
| EP-1605979-B1 | CONJUGATES FOR MEDICAL IMAGING COMPRISING CARRIER, TARGETING MOIETY AND A CONTRAST AGENT | UPPERTON LTD (GB) | 2008-10-22 | — | — | EP | claimed |
| JP-2006518727-A | — | — | 2006-08-17 | — | — | JP | claimed |
| US-20060171892-A1 | Conjugates for medical imaging comprising carrier, targetting moiety and a contrast agent | NOVOZYMES BIOPHARMA UK LIMITED (GB) | 2006-08-03 | — | — | US | claimed |
| EP-1605979-A1 | CONJUGATES FOR MEDICAL IMAGING COMPRISING CARRIER, TARGETING MOIETY AND A CONTRAST AGENT | Upperton Limited (GB) | 2005-12-21 | — | — | EP | claimed |
| WO-2004071536-A1 | CONJUGATES FOR MEDICAL IMAGING COMPRISING CARRIER, TARGETING MOIETY AND A CONTRAST AGENT | UPPERTON LIMITED (GB) | 2004-08-26 | — | — | WO | claimed |
| US-11780963-B2 | Multi-arm multi-claw polyethylene glycol derivative suitable for click chemistry reactions | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2023-10-10 | — | — | US | disclosed |
| US-20230105468-A1 | CONJUGATION METHODS | IMMUNOGEN, INC. | 2023-04-06 | — | — | US | disclosed |
| US-11053185-B2 | Dendritic polyethylene glycol derivative, and preparation method and application thereof | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2021-07-06 | — | — | US | disclosed |
| US-20210163625-A1 | CONJUGATION METHODS | IMMUNOGEN SWITZERLAND GMBH (CH) | 2021-06-03 | — | — | US | disclosed |
| US-10815309-B2 | Methods for preparing antibody-drug conjugates | IMMUNOGEN, INC. (US) | 2020-10-27 | — | — | US | disclosed |
| US-20200140611-A1 | MULTI-ARM MULTI-CLAW POLYETHYLENE GLYCOL DERIVATIVE SUITABLE FOR CLICK CHEMISTRY REACTIONS | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2020-05-07 | — | — | US | disclosed |
| US-20200131107-A1 | DENDRITIC POLYETHYLENE GLYCOL DERIVATIVE, AND PREPARATION METHOD AND APPLICATION THEREOF | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2020-04-30 | — | — | US | disclosed |
| US-20110142762-A1 | Conjugates for medical imaging comprising carrier, targeting moiety and a contrast agent | NOVOZYMES BIOPHARMA DK A/S (DK) | 2011-06-16 | — | — | US | disclosed |
| US-20110003969-A1 | CONJUGATION METHODS | IMMUNOGEN INC. (US) | 2011-01-06 | — | — | US | disclosed |
| WO-2010141566-A1 | CONJUGATION METHODS | IMMUNOGEN, INC. (US) | 2010-12-09 | — | — | WO | disclosed |
| EP-1605979-B1 | CONJUGATES FOR MEDICAL IMAGING COMPRISING CARRIER, TARGETING MOIETY AND A CONTRAST AGENT | UPPERTON LTD (GB) | 2008-10-22 | — | — | EP | disclosed |
| US-20060171892-A1 | Conjugates for medical imaging comprising carrier, targetting moiety and a contrast agent | NOVOZYMES BIOPHARMA UK LIMITED (GB) | 2006-08-03 | — | — | US | disclosed |
| EP-1605979-A1 | CONJUGATES FOR MEDICAL IMAGING COMPRISING CARRIER, TARGETING MOIETY AND A CONTRAST AGENT | Upperton Limited (GB) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004071536-A1 | CONJUGATES FOR MEDICAL IMAGING COMPRISING CARRIER, TARGETING MOIETY AND A CONTRAST AGENT | UPPERTON LIMITED (GB) | 2004-08-26 | — | — | WO | disclosed |