SCHEMBL914712

SCHEMBL914712

SSc1ccncc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8522944 0.75
SCHEMBL191955 0.73 MEN1 (1.00)
SCHEMBL144087 0.73 DDAH1 (1.00)
SCHEMBL965041 0.71
SCHEMBL19217284 0.69 CYP3A4 (0.47)
SCHEMBL23182834 0.69
SCHEMBL272574 0.69
SCHEMBL272575 0.69
SCHEMBL4114252 0.69
SCHEMBL14790284 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102993220-A 5-bromoisophthalic acid zinc complex and preparation method thereof UNIV LUOYANG NORMAL 2013-03-27 CN claimed
EP-1002066-B1 COMPOSITION AND METHOD FOR REGULATING THE ADHESION OF CELLS AND BIOMOLECULES TO HYDROPHOBIC SURFACES UNIV UTAH RES FOUND (US) 2011-03-09 EP claimed
US-20110008811-A1 Resin Assisted Capture of Cysteine-Modified Proteins/Peptides and Determination of Presence and Location of Modification DUKE UNIVERSITY (US) 2011-01-13 US claimed
WO-2009085106-A1 RESIN ASSISTED CAPTURE OF CYSTEINE-MODIFIED PROTEINS/PEPTIDES AND DETERMINATION OF PRESENCE AND LOCATION OF MODIFICATION DUKE UNIVERSITY (US) 2009-07-09 WO claimed
US-7208299-B2 Composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces UNIVERSTIY OF UTAH RESEARCH FOUNDATION (US) 2007-04-24 US claimed
EP-1002066-A4 COMPOSITION AND METHOD FOR REGULATING THE ADHESION OF CELLS AND BIOMOLECULES TO HYDROPHOBIC SURFACES UNIV UTAH RES FOUND (US) 2004-12-01 EP claimed
US-20040170964-A1 Composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces NAGLER, RICHARD, MR. 2004-09-02 US claimed
EP-1432727-A2 TRIMERIC CONJUGATES OF PEPTIDIC DERIVATIVE AdProTech Limited (GB) 2004-06-30 EP claimed
WO-2003027137-A2 TRIMERIC CONJUGATES OF PEPTIDIC DERIVATIVE ADPROTECH LIMITED (GB) 2003-04-03 WO claimed
US-20020019037-A1 Composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces NAGLER, RICHARD, MR. 2002-02-14 US claimed
US-6284503-B1 ACTIVATING THE END GROUP OF AN ETHYLENE OXIDE-PROPYLENE OXIDE COPOLYMER, ADSORBTION OF THE COPOLYMER ON THE SURFACE, CONJUGATING A THIOL CONTAINING BIOMOLECULE TO THE COPOLYMER AND CONTACTING WITH CELL OR VIRUS TO ADHERE IT UNIVERSITY OF UTAH RESEARCH FOUNDATION 2001-09-04 US claimed
EP-1002066-A1 COMPOSITION AND METHOD FOR REGULATING THE ADHESION OF CELLS AND BIOMOLECULES TO HYDROPHOBIC SURFACES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2000-05-24 EP claimed
WO-1998031734-A1 COMPOSITION AND METHOD FOR REGULATING THE ADHESION OF CELLS AND BIOMOLECULES TO HYDROPHOBIC SURFACES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 1998-07-23 WO claimed
US-20230348369-A1 NAMPT MODULATORS CYTOKINETICS, INC. 2023-11-02 US disclosed
US-9926298-B2 Heterocyclic compounds and use thereof NATIONAL HEALTH RESEARCH INSTITUTES (TW) 2018-03-27 US disclosed
US-9908872-B2 Methods to treat lymphoplasmacytic lymphoma DANA-FARBER CANCER INSTITUTE, INC. (US) 2018-03-06 US disclosed
EP-0115171-A2 Conjugate having cytotoxicity and process for the preparation thereof TEIJIN LIMITED (JP) 1984-08-08 EP disclosed
EP-0112720-A2 Conjugate having cytotoxicity and process for the preparation thereof TEIJIN LIMITED (JP) 1984-07-04 EP disclosed
US-4385169-A Reactive alpha amino acid polymer TEIJIN LIMITED (JP) 1983-05-24 US disclosed
EP-0040506-A2 Reactive polymer and process for the preparation thereof TEIJIN LIMITED (JP) 1981-11-25 EP disclosed