⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23254599 | 0.84 | MAPT (0.55) | — | |
| SCHEMBL914712 | 0.75 | — | — | |
| SCHEMBL144087 | 0.73 | DDAH1 (1.00) | — | |
| SCHEMBL191955 | 0.73 | MEN1 (1.00) | — | |
| SCHEMBL965041 | 0.71 | — | — | |
| SCHEMBL272575 | 0.69 | — | — | |
| SCHEMBL23182834 | 0.69 | — | — | |
| SCHEMBL272574 | 0.69 | — | — | |
| SCHEMBL4114252 | 0.69 | — | — | |
| SCHEMBL177955 | 0.67 | TSHR (0.70) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1223640-A | Substituted N- (4-pyridyl) -thioamides with insecticidal activity | BAYER AG (DE) | 1999-07-21 | — | — | CN | disclosed |
| CN-1223640-A | Substituted N- (4-pyridyl) -thioamides with insecticidal activity | BAYER AG (DE) | 1999-07-21 | — | — | CN | disclosed |
| EP-0907640-A1 | SUBSTITUTED N-(4-PYRIDYL)-THIOAMIDES WITH PESTICIDE ACTIVITY | BAYER AG (DE) | 1999-04-14 | — | — | EP | disclosed |
| WO-1997049683-A1 | SUBSTITUTED N-(4-PYRIDYL)-THIOAMIDES WITH PESTICIDE ACTIVITY | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-31 | — | — | WO | disclosed |