Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | DCTPP1 | Q9H773 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27263187 | 0.88 | DRD4 (0.48) | DRD4TSHR | |
| SCHEMBL27263864 | 0.84 | MAPT (0.53) | ALDH1A1SMN1; SMN2MAPTTP53DRD4 | |
| SCHEMBL27263519 | 0.81 | TIPARP (0.53) | ALDH1A1MAPTDRD4TSHR | |
| SCHEMBL9527840 | 0.79 | HTR1A (0.58) | SMN1; SMN2DCTPP1 | |
| SCHEMBL27263185 | 0.79 | TRPC5 (0.51) | ALDH1A1SMN1; SMN2MAPTTP53DRD4 | |
| SCHEMBL27263412 | 0.78 | ADRA1D (0.52) | ALDH1A1MAPTDRD4TSHR | |
| SCHEMBL27263632 | 0.78 | HTR1A (0.48) | ALDH1A1SMN1; SMN2MAPTTP53DRD4 | |
| SCHEMBL27263188 | 0.77 | DRD4 (0.45) | ALDH1A1SMN1; SMN2MAPTTP53DRD4 | |
| SCHEMBL27263409 | 0.77 | PKM (0.45) | ALDH1A1SMN1; SMN2MAPTHTR7 | |
| SCHEMBL27263196 | 0.76 | DRD4 (0.48) | ALDH1A1MAPTTP53DRD4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1022565-C | Process for preparing piperazinylalkyl-3(2H)-pyridazinones | CL PHARMA (AT) | 1993-10-27 | — | — | CN | disclosed |
| CN-1043129-A | New piperazinyl alkyl-3 (2H)-pyridazinone, its preparation method and as the application of hypotensive agent | CL PHARMA (AT) | 1990-06-20 | — | — | CN | disclosed |