Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.52 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27263874 | 0.86 | ATM (0.47) | ALDH1A1PKMNPC1MAPTSMN1; SMN2 | |
| SCHEMBL27263072 | 0.84 | BPTF (0.46) | BPTFKAT2BBRD4ALDH1A1DRD2 | |
| SCHEMBL27263409 | 0.84 | PKM (0.45) | BPTFKAT2BBRD4ALDH1A1PKM | |
| SCHEMBL27263418 | 0.84 | BRD4 (0.46) | KAT2BBRD4ALDH1A1PKMNPC1 | |
| SCHEMBL27263868 | 0.83 | HTR1A (0.42) | BPTFALDH1A1DRD2HTR2AHRH1 | |
| SCHEMBL27263187 | 0.83 | DRD4 (0.48) | DRD2 | |
| SCHEMBL27263304 | 0.81 | PKM (0.43) | BPTFKAT2BBRD4ALDH1A1PKM | |
| SCHEMBL9528853 | 0.81 | KAT2B (0.60) | BPTFKAT2BBRD4DRD2HTR2A | |
| SCHEMBL27263994 | 0.80 | HTR1A (0.57) | — | |
| SCHEMBL27263295 | 0.80 | ADRA1A (0.55) | ALDH1A1PKMNPC1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1022565-C | Process for preparing piperazinylalkyl-3(2H)-pyridazinones | CL PHARMA (AT) | 1993-10-27 | — | — | CN | disclosed |
| CN-1043129-A | New piperazinyl alkyl-3 (2H)-pyridazinone, its preparation method and as the application of hypotensive agent | CL PHARMA (AT) | 1990-06-20 | — | — | CN | disclosed |