Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27864838 | 0.73 | MAOB (0.40) | ACHE | |
| SCHEMBL8561344 | 0.72 | ACHE (0.39) | METAP1ACHE | |
| SCHEMBL27329755 | 0.66 | MAPT (0.37) | — | |
| SCHEMBL27264157 | 0.66 | KDM4E (0.30) | — | |
| SCHEMBL27329759 | 0.66 | HCRTR1 (0.35) | — | |
| SCHEMBL27953567 | 0.62 | MAOB (0.43) | ACHE | |
| SCHEMBL8561415 | 0.61 | HRH3 (0.43) | — | |
| Hydrochloric Acid SCHEMBL8557411 | 0.61 | OPRK1 (0.43) | — | |
| SCHEMBL13058861 | 0.59 | GLS (0.46) | — | |
| SCHEMBL15354259 | 0.59 | ALDH1A1 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1030450-C | Preparation of analgesic carboxylic acid amides derivative | SANKYO CO (JP) | 1995-12-06 | — | — | CN | disclosed |
| CN-1079741-A | The preparation method of analgesic carboxylic acid amide derivatives | SANKYO CO (JP) | 1993-12-22 | — | — | CN | disclosed |
| CN-1079740-A | The preparation method of analgesic carboxylic acid amide derivatives | SANKYO CO (JP) | 1993-12-22 | — | — | CN | disclosed |
| CN-1078461-A | The preparation method of analgesic carboxylic acid amide derivatives | SANKYO CO (JP) | 1993-11-17 | — | — | CN | disclosed |
| CN-1022185-C | Process for preparing analgesic carboxylic acid amide derivatives | SANKYO CO (JP) | 1993-09-22 | — | — | CN | disclosed |
| CN-1040791-A | ANALGESIC CARBOXYLIC ACID AMIDE DERIVATIVES | SANKYO CO (JP) | 1990-03-28 | — | — | CN | disclosed |