Fluoride

Fluoride

SCHEMBL27267635

F.F.O.[Al+3].[F-].[F-].[F-]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Fluoride. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL2023230 0.87
Fluoride SCHEMBL27486968 0.87
Water SCHEMBL17336047 0.87 CA4 (0.33)
Water SCHEMBL829247 0.87
Fluoride SCHEMBL3397748 0.87
Fluoride SCHEMBL8671306 0.75
Water SCHEMBL3629339 0.75
Fluoride SCHEMBL4809300 0.75
Water SCHEMBL20593975 0.75
Fluoride SCHEMBL1940522 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114988449-A Preparation method of low-oxygen-content anhydrous aluminum fluoride 灵宝市民生高新材料有限公司 2022-09-02 CN disclosed
CN-110337709-A Control of directionality in atomic layer etching 朗姆研究公司 2019-10-15 CN disclosed
CN-109803945-A Composition comprising 1- chloro- 2,2- Difluoroethane and 1,1- dichloroethylene 阿科玛法国公司 2019-05-24 CN disclosed
CN-109790089-A Process for preparing 1-chloro-2, 2-difluoroethane 阿科玛法国公司 2019-05-21 CN disclosed
CN-109311787-A Process for producing tetrafluoropropene 阿科玛法国公司 2019-02-05 CN disclosed
CN-109311788-A The method for producing tetrafluoropropene 阿科玛法国公司 2019-02-05 CN disclosed
CN-109069992-A Hydrochloric acid purification method and apparatus 阿科玛法国公司 2018-12-21 CN disclosed
CN-105367377-B The method for manufacturing the chloro- 3,3,3- trifluoro propenes of 2- by the gas phase fluorination of pentachloropropane 阿克马法国公司 2018-10-30 CN disclosed
CN-108698959-A Azeotropic or quasi-azeotropic compositions comprising trifluoropropyne 阿科玛法国公司 2018-10-23 CN disclosed
CN-108473396-A The method of production and purifying 2,3,3,3- tetrafluoro-1-propenes 阿科玛法国公司 2018-08-31 CN disclosed
CN-103597374-A Transparent glass scintillator, preparation method and application device GEORGIA TECH RES INST 2014-02-19 CN disclosed
CN-103328422-A Process for the manufacture of 2,3,3, 3-tetrafluoropropene by gas phase fluorination of pentachloropropane ARKEMA FRANCE 2013-09-25 CN disclosed
CN-103180275-A Process for the preparation of 2,3,3,3 tetrafluoropropene ARKEMA FRANCE 2013-06-26 CN disclosed
CN-103180276-A Process for the manufacture of 2-chloro-3, 3, 3-trifluoropropene by gas phase fluorination of pentachloropropane ARKEMA FRANCE 2013-06-26 CN disclosed
CN-101380636-B Wet clean process for recovery of anodized chamber parts APPLIED MATERIALS INC 2013-03-27 CN disclosed
CN-102224123-A Process for the preparation of chlorofluoroalkenes SOLVAY FLUOR GMBH 2011-10-19 CN disclosed
CN-101801894-A Prepare halogen-containing and alkene hydrogen by metal fluoride catalysts SOLVAY FLUOR GMBH 2010-08-11 CN disclosed
CN-101380636-A Wet clean process for recovery of anodized chamber parts APPLIED MATERIALS INC (US) 2009-03-11 CN disclosed
CN-1020589-C ISOMERIZATION OF SATURATED FLUOROHYDROCARBONS DU PONT (US) 1993-05-12 CN disclosed
CN-1044088-A The isomerization of saturated fluorohydrocarbons DU PONT (US) 1990-07-25 CN disclosed