Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NOS1 | P29475 | 3/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | SGK1 | O00141 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12102081 | 0.76 | ALDH1A1 (0.38) | KDM4EALDH1A1HPGDNOS1NOS3 | |
| SCHEMBL29016448 | 0.75 | TYMS (0.37) | NOS1NOS3NOS2CSNK2A2CSNK2B | |
| SCHEMBL3454164 | 0.72 | NOS1 (0.53) | LMNAKDM4EALDH1A1HPGDNOS1 | |
| SCHEMBL26018101 | 0.72 | NOS1 (0.32) | KDM4EALDH1A1HPGDNOS1MAPT | |
| SCHEMBL29501873 | 0.71 | NOS1 (0.30) | NOS1NOS3NOS2 | |
| SCHEMBL31561468 | 0.66 | CASP7 (0.34) | LMNAKDM4EALDH1A1HPGDNOS1 | |
| SCHEMBL11683196 | 0.62 | ALDH1A1 (0.42) | LMNAKDM4EALDH1A1HPGDPIK3CB | |
| SCHEMBL11177056 | 0.61 | NUDT1 (0.40) | LMNAKDM4EALDH1A1HPGDNOS1 | |
| SCHEMBL3781351 | 0.58 | — | — | |
| SCHEMBL31556103 | 0.58 | ALDH1A1 (0.50) | LMNAKDM4EALDH1A1HPGDNOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012058293-A1 | METHODS OF SACCHARIFYING SUGARCANE TRASH | NOVOZYMES NORTH AMERICA, INC. (US) | 2012-05-03 | — | — | WO | disclosed |