Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 12/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KLK1 | P06870 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19300037 | 0.89 | HSD17B10 (0.51) | KLKB1HSD17B10ALDH1A1LMNAHTT | |
| SCHEMBL948453 | 0.88 | HSD17B10 (0.61) | KLKB1HSD17B10ALDH1A1LMNAPOLB | |
| SCHEMBL949612 | 0.88 | KLKB1 (0.53) | KLKB1HSD17B10ALDH1A1LMNAPOLB | |
| SCHEMBL17229366 | 0.88 | KLKB1 (0.51) | KLKB1HSD17B10ALDH1A1LMNAHTT | |
| SCHEMBL27286142 | 0.86 | HSD17B10 (0.68) | KLKB1HSD17B10ALDH1A1LMNAHTT | |
| SCHEMBL752774 | 0.86 | LMNA (0.61) | KLKB1HSD17B10ALDH1A1LMNAHTT | |
| SCHEMBL17696410 | 0.86 | KLKB1 (0.55) | KLKB1HSD17B10ALDH1A1LMNAPOLB | |
| SCHEMBL13692389 | 0.86 | L3MBTL1 (0.54) | KLKB1HSD17B10ALDH1A1LMNAHTT | |
| SCHEMBL19299983 | 0.84 | KLKB1 (0.47) | KLKB1HSD17B10ALDH1A1LMNAHTT | |
| SCHEMBL27259482 | 0.84 | KLKB1 (0.51) | KLKB1HSD17B10ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026483-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |