Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27376022 | 0.90 | L3MBTL1 (0.47) | LMNAALDH1A1NPBWR1AGTR1AGTR2 | |
| SCHEMBL27286278 | 0.86 | LMNA (0.37) | LMNAALDH1A1NPBWR1AGTR1AGTR2 | |
| SCHEMBL27378931 | 0.85 | NPBWR1 (0.43) | LMNAALDH1A1NPBWR1AGTR1AGTR2 | |
| SCHEMBL27286147 | 0.85 | L3MBTL1 (0.43) | LMNAALDH1A1KDM4EPOLBHPGD | |
| SCHEMBL19087043 | 0.84 | ALDH1A1 (0.53) | LMNAALDH1A1NPBWR1AGTR1AGTR2 | |
| SCHEMBL30736732 | 0.83 | NPBWR1 (0.41) | LMNAALDH1A1NPBWR1AGTR1AGTR2 | |
| SCHEMBL19077852 | 0.82 | NPBWR1 (0.46) | LMNAALDH1A1NPBWR1AGTR1AGTR2 | |
| SCHEMBL27286140 | 0.79 | ALDH1A1 (0.62) | LMNAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL30736709 | 0.77 | L3MBTL1 (0.44) | LMNAALDH1A1POLBHPGDMAPT | |
| SCHEMBL27286280 | 0.75 | MAOA (0.49) | ALDH1A1KDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026486-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| WO-2024026484-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |