SCHEMBL27286641

SCHEMBL27286641

CS(=O)(=O)c1c(C(=O)O)ccc(C(F)(F)F)c1N

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
KDM4E B2RXH2 2/20 0.45
HPGD P15428 2/20 0.45
HSD17B10 Q99714 2/20 0.45
ALOX15 P16050 1/20 0.39
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CFTR P13569 1/20 0.35
NOTUM Q6P988 2/20 0.35
KIF11 P52732 1/20 0.35
TAS2R14 Q9NYV8 1/20 0.35
DAO P14920 1/20 0.34
ASPH Q12797 1/20 0.34
LMNA P02545 1/20 0.34
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34
USP2 O75604 1/20 0.34
CYP2C19 P33261 1/20 0.34
CES2 O00748 2/20 0.33
GABRP O00591 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL977553 0.83 ALOX15 (0.40) ALDH1A1KDM4EHPGDHSD17B10ALOX15
SCHEMBL1635205 0.79 TAS2R14 (0.41) ALDH1A1KDM4EHPGDHSD17B10ALOX15
SCHEMBL978102 0.79 ALDH1A1 (0.38) ALDH1A1KDM4EHPGDHSD17B10ALOX15
SCHEMBL28488432 0.79 ALOX15 (0.37) ALDH1A1KDM4EHPGDHSD17B10ALOX15
SCHEMBL1223395 0.77 KDM4E (0.46) ALDH1A1KDM4EHPGDHSD17B10MEN1
SCHEMBL27329120 0.77 ALOX15 (0.43) ALDH1A1KDM4EHPGDHSD17B10ALOX15
SCHEMBL31121874 0.73 KDM4E (0.46) ALDH1A1KDM4EHPGDHSD17B10CFTR
SCHEMBL21179417 0.73 KDM4E (0.46) ALDH1A1KDM4EHPGDHSD17B10CFTR
SCHEMBL2477406 0.73 TAS2R14 (0.48) ALDH1A1KDM4EHPGDHSD17B10MEN1
SCHEMBL27757012 0.73 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDHSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1037437-C New herbicides RHONE POULENC AGRICULTURE 1998-02-18 CN disclosed
CN-1089258-A New herbicides RHONE POULENC AGRICULTURE (GB) 1994-07-13 CN disclosed