Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.36 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL977553 | 0.80 | ALOX15 (0.40) | ALDH1A1MEN1KMT2AKDM4EALOX15 | |
| SCHEMBL27286641 | 0.79 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AKDM4EALOX15 | |
| SCHEMBL976634 | 0.79 | L3MBTL1 (0.34) | KMT2ARBP4CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1635205 | 0.77 | TAS2R14 (0.41) | ALDH1A1MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL28488432 | 0.77 | ALOX15 (0.37) | ALDH1A1MEN1KMT2AKDM4EALOX15 | |
| SCHEMBL17672966 | 0.73 | TAS2R14 (0.54) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL27809355 | 0.73 | DRD2 (0.30) | — | |
| SCHEMBL978250 | 0.73 | CYP11B1 (0.32) | KMT2A | |
| SCHEMBL28237620 | 0.70 | CTSS (0.35) | MAPTSMN1; SMN2CLCN2NOTUMKIF11 | |
| SCHEMBL21416407 | 0.68 | KIF11 (0.36) | KMT2ATAS2R14KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188009-B2 | 4-(3-aminobenzoyl)-5-cyclopropylisoxazoles effective as herbicides | BAYER CROPSCIENCE AG (DE) | 2012-05-29 | — | — | US | disclosed |
| EP-2260027-B1 | 4-(3-AMINOBENZOYL)-5-CYCLOPROPYLISOXAZOLES EFFECTIVE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2011-06-29 | — | — | EP | disclosed |
| CN-101981016-A | Effective herbicide 4- (3-aminobenzoyl) -5-cyclopropyl isoxazole | BAYER CROPSCIENCE AG | 2011-02-23 | — | — | CN | disclosed |
| US-20110015073-A1 | 4-(3-AMINOBENZOYL)-5-CYCLOPROPYLISOXAZOLES EFFECTIVE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2011-01-20 | — | — | US | disclosed |
| EP-2260027-A1 | 4-(3-AMINOBENZOYL)-5-CYCLOPROPYLISOXAZOLES EFFECTIVE AS HERBICIDES | Bayer CropScience AG (DE) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009118125-A1 | 4-(3-AMINOBENZOYL)-5-CYCLOPROPYLISOXAZOLES EFFECTIVE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2009-10-01 | — | — | WO | disclosed |
| EP-2105437-A1 | 4-(3-Aminobenzoyl)-5-cyclopropylisoxazols as herbicides | Bayer CropScience Aktiengesellschaft (DE) | 2009-09-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015073-A1 | 4-(3-AMINOBENZOYL)-5-CYCLOPROPYLISOXAZOLES EFFECTIVE AS HERBICIDES | CYP4X1, PRDX4, PRDX5 | ALDH1A1 426/4885MEN1 4795/4885KMT2A 1230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.