Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713912 | 0.84 | CA12 (0.53) | PTGS1PTGS2LMNACA12CA1 | |
| SCHEMBL6723569 | 0.84 | CA12 (0.53) | PTGS1PTGS2LMNACA12CA1 | |
| SCHEMBL27390681 | 0.77 | EPHX1 (0.56) | PTGS2EPHX1LMNAHPGDGAA | |
| SCHEMBL7346532 | 0.74 | EPHX2 (0.40) | EPHX1CA12CA1CA2CA4 | |
| SCHEMBL28565924 | 0.71 | PTGDR2 (0.47) | PTGS1PTGS2EPHX1LMNAKMT2A | |
| SCHEMBL10585500 | 0.70 | CA1 (0.53) | PTGS1LMNACA12CA1CA2 | |
| SCHEMBL2653447 | 0.69 | PTGDR2 (0.44) | PTGS1PTGS2EPHX1LMNAHPGD | |
| SCHEMBL9319561 | 0.69 | EPHX1 (0.49) | PTGS1PTGS2EPHX1LMNAHPGD | |
| SCHEMBL7546509 | 0.68 | EPHX2 (0.46) | EPHX1HPGDSMN1; SMN2TSHRRAB9A | |
| SCHEMBL2209026 | 0.68 | PTGS2 (0.44) | PTGS1PTGS2LMNAHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1046525-C | Compounds containing a fused bicyclic ring and processes therefor | BRISTOL MYERS SQUIBB CO (US) | 1999-11-17 | — | — | CN | disclosed |
| CN-1039008-C | Dual action inhibitors | SQUIBB & SONS INC (US) | 1998-07-08 | — | — | CN | disclosed |
| CN-1099392-A | Compounds containing a fused bicyclic ring and processes therefor | BRISTOL MYERS SQIBB COMPANY (US) | 1995-03-01 | — | — | CN | disclosed |
| CN-1084849-A | Dual action inhibitors | SQUIBB & SONS INC (US) | 1994-04-06 | — | — | CN | disclosed |