Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27619659 | 0.82 | MAPT (0.51) | MAPTSMN1; SMN2LMNAPTGESDHFR | |
| SCHEMBL13265727 | 0.79 | GUSB (0.48) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL2418894 | 0.78 | SMN1; SMN2 (0.52) | MAPTSMN1; SMN2LMNADHFRMEN1 | |
| SCHEMBL2853747 | 0.77 | SIRT1 (0.47) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL13240455 | 0.76 | LMNA (0.62) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL2807223 | 0.74 | TRPA1 (0.54) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL2963062 | 0.74 | LMNA (0.64) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL13240454 | 0.73 | LMNA (0.62) | MAPTSMN1; SMN2LMNADHFRMEN1 | |
| SCHEMBL27912267 | 0.73 | SIRT1 (0.66) | MAPTSMN1; SMN2LMNADHFRMEN1 | |
| SCHEMBL2954723 | 0.72 | SMN1; SMN2 (0.58) | MAPTSMN1; SMN2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1038413-C | Therapeutic amides | ZENECA LTD (GB) | 1998-05-20 | — | — | CN | disclosed |