Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 1/20 | 0.48 |
| ▸ | DDX3X | O00571 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NFKBIA | P25963 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13265928 | 0.81 | DDX3X (0.57) | DDX3XNFKBIARELAMAPTSMN1; SMN2 | |
| SCHEMBL13265730 | 0.81 | ALDH1A1 (0.51) | GUSBMAPTLMNAMEN1KMT2A | |
| SCHEMBL13265978 | 0.79 | DDX3X (0.46) | DDX3XTBXA2RNFKBIARELAMAPT | |
| SCHEMBL27290714 | 0.79 | MAPT (0.51) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL13240458 | 0.78 | CA2 (0.61) | GUSBTBXA2RPKMMAPTSMN1; SMN2 | |
| SCHEMBL13265847 | 0.74 | ALDH1A1 (0.51) | GUSBPKMMAPTSMN1; SMN2LMNA | |
| SCHEMBL13265731 | 0.74 | MEN1 (0.49) | PKMMAPTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL13265719 | 0.73 | HPGD (0.46) | GUSBMAPTLMNAMEN1KMT2A | |
| SCHEMBL13265862 | 0.72 | ALPL (0.56) | GUSBPKMMAPTSMN1; SMN2LMNA | |
| SCHEMBL14537875 | 0.70 | DDX3X (0.57) | DDX3XNFKBIARELAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754773-B2 | Composition and synthesis of new reagents for inhibition of HIV replication | UNIVERSITY OF MASSACHUSETTS (US) | 2010-07-13 | — | — | US | disclosed |
| US-20070099919-A1 | Composition and synthesis of new reagents for inhibition of HIV replication | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099919-A1 | Composition and synthesis of new reagents for inhibition of HIV replication | REV1, MAVS, ISG15 | GUSB 3771/4885DDX3X 322/4885TBXA2R 4415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.