SCHEMBL4067323

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4067417	0.88	MAPT (0.49)	MAPTALDH1A1MAPK1LMNAHTT
	SCHEMBL1266996	0.86	MAPT (0.59)	MAPTALDH1A1MAPK1LMNAHTT
	SCHEMBL4565389	0.81	MAPK1 (0.48)	MAPTALDH1A1MAPK1LMNAHTT
	Hydrochloric Acid SCHEMBL6368616	0.79	MAPK1 (0.47)	MAPTALDH1A1MAPK1LMNAHTT
	SCHEMBL4071866	0.78	ADRB1 (0.50)	MAPTALDH1A1LMNAHTTTDP1
	SCHEMBL2127395	0.78	MAPT (0.52)	MAPTALDH1A1MAPK1LMNAHTT
	SCHEMBL4068045	0.78	HTR3E (0.50)	MAPTALDH1A1LMNAHTTGFER
	SCHEMBL6399527	0.78	MAPT (0.46)	MAPTALDH1A1LMNAGFERTDP1
	SCHEMBL4065775	0.78	MAOB (0.38)	—
	SCHEMBL4069611	0.78	CA12 (0.46)	ALDH1A1LMNAKDM4ECA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.