Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 2/20 | 0.49 |
| ▸ | Q9HBH1 | 1/20 | 0.48 | |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24101471 | 0.90 | PDF (0.45) | FURINPDFKLKB1SSTR3SPHK1 | |
| SCHEMBL27291534 | 0.88 | FURIN (0.48) | FURINPDFKLKB1SSTR3TP53 | |
| SCHEMBL27291530 | 0.86 | FURIN (0.51) | FURINPDFKLKB1SSTR3TP53 | |
| SCHEMBL27291528 | 0.86 | FURIN (0.49) | FURINSPHK1TP53SMN1; SMN2MEN1 | |
| SCHEMBL17424310 | 0.86 | SPHK1 (0.51) | PDFKLKB1SSTR3SPHK1PLG | |
| SCHEMBL24393479 | 0.80 | PDF (0.44) | FURINPDFKLKB1SSTR3PLG | |
| SCHEMBL21234897 | 0.80 | FURIN (0.48) | FURINPDFKLKB1SSTR3TP53 | |
| SCHEMBL15099992 | 0.80 | SMN1; SMN2 (0.48) | SPHK1TP53SMN1; SMN2MEN1KMT2A | |
| SCHEMBL24864487 | 0.79 | KLKB1 (0.44) | FURINPDFKLKB1SSTR3PLG | |
| SCHEMBL21965275 | 0.79 | FURIN (0.41) | FURINSPHK1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207429-A1 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2024-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240207429-A1 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PAICS, DHFR, CD44 | FURIN 34/4885PDF 297/4885KLKB1 2818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.