1-Naphthalenylthiazole

1-Naphthalenylthiazole

SCHEMBL272929

c1ccc2c(-c3nccs3)cccc2c1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.53
PDPK1 O15530 1/20 0.50
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
TGFBR1 P36897 2/20 0.43
HSP90AA1 P07900 2/20 0.43
ADORA2A P29274 1/20 0.43
ADORA1 P30542 1/20 0.43
KDM4E B2RXH2 3/20 0.43
ALDH1A1 P00352 2/20 0.43
MAPT P10636 2/20 0.43
HPGD P15428 2/20 0.43
MAPK1 P28482 2/20 0.43
HSD17B10 Q99714 2/20 0.43
NPC1 O15118 1/20 0.43
TP53 P04637 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
DCTPP1 Q9H773 1/20 0.43
AR P10275 1/20 0.41
SYK P43405 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26259560 0.90 PDPK1 (0.54) RAB9APDPK1TGFBR1HSP90AA1ADORA2A
SCHEMBL26259375 0.86 PDPK1 (0.59) RAB9APDPK1TGFBR1HSP90AA1ADORA2A
SCHEMBL4722041 0.84 RAB9A (0.49) RAB9APDPK1TGFBR1HSP90AA1ADORA2A
SCHEMBL3124010 0.83 MAPK8 (0.49) RAB9APDPK1HSP90AA1KDM4EAR
SCHEMBL5692672 0.82 PDPK1 (0.64) RAB9APDPK1TGFBR1HSP90AA1ADORA2A
SCHEMBL26259717 0.81 HSD17B10 (0.54) RAB9APDPK1HSP90AA1ADORA2AADORA1
SCHEMBL6651731 0.81 PRKCZ (0.47) RAB9APDPK1TGFBR1ADORA2AADORA1
SCHEMBL1951149 0.80 PDPK1 (0.61) RAB9APDPK1TGFBR1HSP90AA1ADORA2A
SCHEMBL17164239 0.79 TGFBR1 (0.50) RAB9APDPK1MEN1KMT2ATGFBR1
SCHEMBL16159636 0.79 RAB9A (0.54) RAB9APDPK1TGFBR1HSP90AA1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6762 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260096343-A1 MIXTURE, COMPOSITION, ELECTROLUMINESCENT DEVICE AND ELECTRONIC DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2026-04-02 US claimed
US-20250374745-A1 MIXTURE AND COMPOSITION COMPRISING AN ARYLAMINE COMPOUND, ELECTROLUMINESCENT DEVICE AND ELECTRONIC DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2025-12-04 US claimed
EP-4601448-A2 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME Samsung Display Co., Ltd. (KR) 2025-08-13 EP claimed
US-12389792-B2 Light-emitting device and electronic apparatus including the same SAMSUNG DISPLAY CO., LTD. (KR) 2025-08-12 US claimed
EP-4210453-B1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2025-07-16 EP claimed
US-20250186420-A1 POLYMETHINIUM SALTS AS INHIBITORS OF DIHYDROOROTATE DEHYDROGENASE UNIVERZITA KARLOVA (CZ) 2025-06-12 US claimed
EP-4297549-B1 LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2025-02-26 EP claimed
CN-115989214-B Pigment composition, inkjet recording method, image recorded matter, and pigment compound 富士胶片株式会社 2025-02-25 CN claimed
WO-2025023698-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 진웅산업 2025-01-30 WO claimed
EP-4482492-A1 POLYMETHINIUM SALTS AS INHIBITORS OF DIHYDROOROTATE DEHYDROGENASE Univerzita Karlova (CZ) 2025-01-01 EP claimed
US-3973969-A Silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JA) 1976-08-10 US claimed
US-3970459-A Process for developing a direct reversal silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US claimed
US-3970461-A Fogged, direct-positive silver halide emulsion containing carbocyanine dye having indolenine nucleus FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US claimed
US-3969350-A Base catalysis of azolesulfenamides and sulfur to aminodithioazoles MONSANTO COMPANY (US) 1976-07-13 US claimed
US-3966477-A Spectrally sensitized silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JA) 1976-06-29 US claimed
US-3966706-A 2,6-Dihydroxy-3-cyano-4-methylpyridine containing azo dyes which contain a functional amino group CIBA-GEIGY AG (CH) 1976-06-29 US claimed
US-3953216-A BENZOXAZOLES, NAPHTHOXAZOLES FUJI PHOTO FILM CO., LTD. (JA) 1976-04-27 US claimed
US-3953215-A X-RAY FILM FUJI PHOTO FILM CO., LTD. (JA) 1976-04-27 US claimed
US-3945832-A Fogged, direct-positive silver halide emulsion containing desensitizers and a dimethine optical sensitizing dye FUJI PHOTO FILM CO., LTD. (JA) 1976-03-23 US claimed
US-3936308-A Photographic emulsions containing methine dyes having a 1H-imidazo[4,5-b]pyrazine nucleus EASTMAN KODAK COMPANY (US) 1976-02-03 US claimed