Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.51 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | FDFT1 | P37268 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538312 | 0.92 | FDFT1 (0.43) | LTA4HCETPFDFT1 | |
| SCHEMBL7228238 | 0.88 | FDFT1 (0.46) | FDFT1P2RX3 | |
| SCHEMBL27259109 | 0.86 | MAPK1 (0.40) | LTA4HCETPFDFT1P2RX3MGLL | |
| SCHEMBL10719626 | 0.85 | FDFT1 (0.46) | FDFT1 | |
| Silafluofen SCHEMBL27295 | 0.83 | LTA4H (0.43) | LTA4HLMNAGAAMAPT | |
| Silafluofen SCHEMBL8880052 | 0.83 | LTA4H (0.43) | LTA4HLMNAGAAMAPT | |
| SCHEMBL204914 | 0.81 | LTA4H (0.51) | LTA4HCETPFFAR1FFAR4MGLL | |
| SCHEMBL10554911 | 0.81 | LTA4H (0.51) | LTA4HCETPFFAR1FFAR4MGLL | |
| SCHEMBL7525556 | 0.78 | LTA4H (0.54) | LTA4HCETPFFAR1FFAR4MGLL | |
| SCHEMBL9231872 | 0.77 | LTA4H (0.53) | LTA4HLMNAGAAMAPTMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61087687-A | — | — | None | — | — | JP | disclosed |
| US-6699853-B2 | PROTECTING USEFUL PLANTS AGAINST THE UNDESIRABLE ACTION OF HARMFUL INSECTS, ACARIDS AND NEMATODES, | HOECHST SCHERING AGREVO GMBH (DE) | 2004-03-02 | — | — | US | disclosed |
| US-20030162812-A1 | 4-haloalkyl-3-heterocyclylpyridines, 4-haloalkyl-5-heterocyclyl-pyrimidines and 4-trifluoromethyl-3-oxadiazolylpyridines, processes for their preparation, compositions comprising them, and their use as pesticides | HARMSEN SVEN (DE) | 2003-08-28 | — | — | US | disclosed |
| US-6596727-B1 | Substituted 4-amino- and 4-alkoxy-cycloalkylpyrimidines, processes for their preparation, and their use as pesticides and fungicides control of pests and as fungicides. | HOECHST AKTIENGESELLSCHAFT (DE) | 2003-07-22 | — | — | US | disclosed |
| US-6521610-B2 | For controlling harmful insects, acarina and nematodes | HOECHST SCHERING AGREVO GMBH (DE) | 2003-02-18 | — | — | US | disclosed |
| US-20020013326-A1 | 4-Haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclyl-pyrimidines, processes for their preparation, compositions comprising them, and their use as pesticides | TIEBES JORG (DE) | 2002-01-31 | — | — | US | disclosed |
| US-6281221-B1 | Substituted 1,3-dioxan-5-ylamino-hererocyclic compounds, processes for their preparation and their use as pest control compositions | HOECHST SCERING AGREVO GMBH (DE) | 2001-08-28 | — | — | US | disclosed |
| US-6265398-B1 | INSECTICIDES, FUNGICIDES, ANTIFERTILITY AGENTS | HOECHST SCHERING AGREVO GMBH (DE) | 2001-07-24 | — | — | US | disclosed |
| US-6239160-B1 | 4-haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclylpyrimidines, processes for their preparation, compositions comprising them, and their use as pesticides | HOECHST SCHERING AGREVO GMBH (DE) | 2001-05-29 | — | — | US | disclosed |
| US-6207668-B1 | FOR CONTROLLING INSECTS OR THEIR EGGS; AS FUNGICIDES, OVICIDES OR AS VETERINARY MEDICAMENTS | HOECHST SCHERING (DE) | 2001-03-27 | — | — | US | disclosed |
| WO-1993006091-A1 | SUBSTITUED 4-ALKOXYPYRIMIDINES, A PROCESS FOR PREPARING THE SAME, AGENTS CONTAINING THE SAME AND THEIR USE AS PEST CONTROL AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-04-01 | — | — | WO | disclosed |
| US-5162327-A | PYRIMIDINETRIONE DERIVATIVES, AGENTS CONTAINING THEM AND THEIR USE AS AGENTS FOR COMBATING PESTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-10 | — | — | US | disclosed |
| US-5116826-A | SILAZANEOPHYL SULFIDES, AND THEIR USE AS PESTICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-05-26 | — | — | US | disclosed |
| US-5002957-A | Insecticides, acaricides, nematocides | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-03-26 | — | — | US | disclosed |
| US-4990621-A | Insecticides, miticides and nematocides; 3-(3-fluoro-4-phenoxyphenyl, 3-(5-fluoro-3-phenoxypyrid-2-yl) or 3-(3-methyl-4-phenyl prop-1-ene | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| US-4954529-A | MITICIDES, INSECTICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-09-04 | — | — | US | disclosed |
| EP-0224024-B1 | SILANE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THEM AND THEIR USE AS PESTICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-20 | — | — | EP | disclosed |
| EP-0336199-A1 | Azaneophyl and silazaneophyl sulfides, process for their preparation, agents containing them, and their use as pesticides | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-10-11 | — | — | EP | disclosed |
| US-4864027-A | INSECTICIDES, NEMATOCIDES, MITICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | disclosed |
| JP-S6187687-A | INSECTICIDE AND ACARICIDE CONTAINING ORGANOSILICON AROMATIC ALKANE DERIVATIVE AND THEIR PRODUCTION | KATSUTA YOSHIO | 1986-05-06 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162812-A1 | 4-haloalkyl-3-heterocyclylpyridines, 4-haloalkyl-5-heterocyclyl-pyrimidines and 4-trifluoromethyl-3-oxadiazolylpyridines, processes for their preparation, compositions comprising them, and their use as pesticides | DDT, HCK, HPD | LTA4H 447/4885CETP 3816/4885FFAR1 4314/4885 |
| US-20020013326-A1 | 4-Haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclyl-pyrimidines, processes for their preparation, compositions comprising them, and their use as pesticides | DDT, HAX1, HDHD5 | LTA4H 1078/4885CETP 3968/4885FFAR1 4107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.