Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL632013 | 0.78 | MMP8 (0.45) | MMP8MEN1KMT2ATAAR1ALDH1A1 | |
| SCHEMBL9514878 | 0.78 | ALDH1A1 (0.55) | MMP8MEN1KMT2AALDH1A1PKM | |
| SCHEMBL9514909 | 0.73 | MEN1 (0.49) | MMP8MEN1KMT2AALDH1A1PKM | |
| SCHEMBL10588010 | 0.71 | ALDH1A1 (0.61) | MEN1KMT2ATAAR1ALDH1A1PKM | |
| SCHEMBL7275509 | 0.69 | CYP1A2 (0.53) | MEN1KMT2ATAAR1LMNAEPHX1 | |
| SCHEMBL15110433 | 0.69 | MEN1 (0.50) | MEN1KMT2AALDH1A1LMNAF10 | |
| SCHEMBL1553262 | 0.68 | L3MBTL1 (0.54) | MEN1KMT2AFKBP1ALMNAPRMT5 | |
| SCHEMBL29003413 | 0.67 | LMNA (0.47) | MEN1KMT2AALDH1A1FKBP1ALMNA | |
| SCHEMBL15573854 | 0.66 | KCNA5 (0.43) | MMP8ALDH1A1FKBP1ALMNAPOLB | |
| SCHEMBL8591876 | 0.66 | KCNA5 (0.42) | ALDH1A1LMNAPRMT5WDR77NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1027271-C | Preparation method of n-statinib and n-cyclostatini polypeptide | PFICER CO LTD (US) | 1995-01-04 | — | — | CN | disclosed |
| CN-87101499-A | Preparation method of n-statinib and n-cyclostatini polypeptide | — | 1988-05-11 | — | — | CN | disclosed |