Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9514909 | 0.86 | MEN1 (0.49) | ALDH1A1PKMMAPTLMNANPSR1 | |
| SCHEMBL7334247 | 0.81 | ALDH1A1 (0.77) | ALDH1A1PKMMAPTALOX15SMN1; SMN2 | |
| SCHEMBL908487 | 0.80 | LMNA (0.55) | ALDH1A1PKMMAPTALOX15SMN1; SMN2 | |
| SCHEMBL9074064 | 0.78 | ALDH1A1 (0.63) | ALDH1A1PKMMAPTALOX15SMN1; SMN2 | |
| SCHEMBL6571504 | 0.78 | ALDH1A1 (0.63) | ALDH1A1PKMMAPTALOX15SMN1; SMN2 | |
| SCHEMBL19621077 | 0.78 | ALDH1A1 (0.63) | ALDH1A1PKMMAPTALOX15SMN1; SMN2 | |
| SCHEMBL7280926 | 0.78 | LMNA (0.68) | ALDH1A1PKMMAPTALOX15SMN1; SMN2 | |
| SCHEMBL9516925 | 0.78 | LMNA (0.68) | ALDH1A1PKMMAPTALOX15SMN1; SMN2 | |
| SCHEMBL27312976 | 0.78 | MMP8 (0.38) | ALDH1A1PKMLMNANPSR1KMT2A | |
| SCHEMBL9074197 | 0.77 | ALDH1A1 (0.61) | ALDH1A1PKMMAPTALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266950-B1 | Nor-statine and nor-cyclostatine polypeptides | PFIZER (US) | 1993-12-29 | — | — | EP | disclosed |
| US-5034376-A | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1991-07-23 | — | — | US | disclosed |
| US-4935405-A | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1990-06-19 | — | — | US | disclosed |
| US-4814342-A | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1989-03-21 | — | — | US | disclosed |
| EP-0266950-A2 | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1988-05-11 | — | — | EP | disclosed |