Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | STAT6 | P42226 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ASAH1 | Q13510 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250113 | 0.80 | SMN1; SMN2 (0.58) | SMN1; SMN2LMNASTAT6ALDH1A1MAPT | |
| SCHEMBL29833599 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNASTAT6ALDH1A1MAPT | |
| SCHEMBL29833600 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNASTAT6ALDH1A1MAPT | |
| SCHEMBL6028992 | 0.77 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNASTAT6ALDH1A1MAPT | |
| SCHEMBL12489824 | 0.75 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL28377896 | 0.73 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNASTAT6ALDH1A1MAPT | |
| SCHEMBL29585279 | 0.73 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNASTAT6ALDH1A1MAPT | |
| SCHEMBL3078847 | 0.73 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNASTAT6ALDH1A1MAPT | |
| SCHEMBL28073614 | 0.72 | ASAH1 (0.61) | SMN1; SMN2LMNASTAT6ALDH1A1MAPT | |
| SCHEMBL12487150 | 0.72 | ALDH1A1 (0.64) | SMN1; SMN2LMNAALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024091542-A1 | COMPOUNDS AND COMPOSITIONS AS GPR52 MODULATORS | NEUROCRINE BIOSCIENCES, INC. (US) | 2024-05-02 | — | — | WO | disclosed |
| WO-2024091542-A1 | COMPOUNDS AND COMPOSITIONS AS GPR52 MODULATORS | NEUROCRINE BIOSCIENCES, INC. (US) | 2024-05-02 | — | — | WO | disclosed |