SCHEMBL27314992

SCHEMBL27314992

C=C(CC)C(OC(=O)Nc1cc(OC(C)C)c(Cl)cc1F)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 11/20 0.37
GAA P10253 2/20 0.37
MAPK1 P28482 1/20 0.37
RORC P51449 1/20 0.36
MAPT P10636 4/20 0.35
LMNA P02545 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
KCNQ3 O43525 1/20 0.34
KCNQ2 O43526 1/20 0.34
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HTT P42858 1/20 0.33
RECQL P46063 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27325182 0.90 HTT (0.37) DHODHGAAMAPK1RORCMAPT
SCHEMBL27365360 0.89 ALDH1A1 (0.43) GAAMAPTLMNAMEN1KMT2A
SCHEMBL27350033 0.88 DHODH (0.38) DHODHGAAMAPK1RORCMAPT
SCHEMBL27344658 0.84 SMN1; SMN2 (0.41) DHODHGAAMAPK1RORCMAPT
SCHEMBL9836714 0.81 LMNA (0.41) DHODHGAAMAPK1RORCMAPT
SCHEMBL9835444 0.81 RORC (0.39) DHODHGAAMAPK1RORCMAPT
SCHEMBL9836355 0.81 ALDH1A1 (0.46) GAAMAPTLMNAMEN1KMT2A
SCHEMBL27315901 0.80 LMNA (0.36) DHODHGAAMAPK1RORCMAPT
SCHEMBL9836348 0.80 RORC (0.37) DHODHGAAMAPK1RORCMAPT
SCHEMBL9836710 0.79 RECQL (0.38) DHODHGAAMAPK1RORCMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1027069-C Process for producing oxazolidinedione derivative SAGAMI CHEM RES (JP) 1994-12-21 CN disclosed
CN-1059718-A The weedicide that contains the  oxazolidinedione derivatives SAGAMI CHEM RES (JP) 1992-03-25 CN disclosed
CN-86108416-A Oxazolidinedione derivative, process for producing the same, and herbicide containing the same 1987-07-29 CN disclosed