SCHEMBL27365360

SCHEMBL27365360

C=C(CC)C(OC(=O)Nc1cc(OC)c(Cl)cc1F)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.43
LMNA P02545 3/20 0.43
NPSR1 Q6W5P4 3/20 0.43
TSHR P16473 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
NPC1 O15118 1/20 0.41
MAPT P10636 1/20 0.41
RAB9A P51151 1/20 0.41
POLB P06746 1/20 0.41
TP53 P04637 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
PYGL P06737 1/20 0.38
KDM4E B2RXH2 3/20 0.38
GAA P10253 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9836355 0.91 ALDH1A1 (0.46) ALDH1A1LMNANPSR1TSHRL3MBTL1
SCHEMBL27350033 0.90 DHODH (0.38) ALDH1A1LMNANPSR1L3MBTL1NPC1
SCHEMBL27314992 0.89 DHODH (0.37) LMNANPSR1NPC1MAPTRAB9A
SCHEMBL9836710 0.83 RECQL (0.38) ALDH1A1LMNANPSR1TSHRL3MBTL1
SCHEMBL9836734 0.82 LMNA (0.36) ALDH1A1LMNANPSR1TSHRL3MBTL1
SCHEMBL9835450 0.81 NPSR1 (0.43) ALDH1A1LMNANPSR1TSHRL3MBTL1
SCHEMBL27325182 0.80 HTT (0.37) ALDH1A1LMNANPSR1TSHRL3MBTL1
SCHEMBL9836957 0.75 TSHR (0.39) ALDH1A1LMNANPSR1TSHRL3MBTL1
SCHEMBL9427372 0.74 LMNA (0.34) ALDH1A1LMNANPSR1TSHRL3MBTL1
SCHEMBL9835963 0.73 RORC (0.39) ALDH1A1LMNANPSR1TSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1059718-A The weedicide that contains the  oxazolidinedione derivatives SAGAMI CHEM RES (JP) 1992-03-25 CN disclosed