Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NNMT | P40261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28154526 | 0.84 | ALPL (0.54) | MAPK1LMNATDP1ALPLCA9 | |
| SCHEMBL30107039 | 0.82 | MAPK1 (0.70) | MAPK1LMNAALPLCYP1A2MAPT | |
| SCHEMBL30341948 | 0.82 | NNMT (0.47) | MAPK1LMNATDP1ALPLCA9 | |
| SCHEMBL17672394 | 0.77 | MAPK1 (0.79) | MAPK1LMNAALPLCYP1A2MAPT | |
| SCHEMBL12011328 | 0.77 | MAPK1 (0.52) | MAPK1ALPLMAPTALDH1A1KDM4E | |
| SCHEMBL27256360 | 0.77 | RAB9A (0.59) | MAPK1LMNAALPLCYP1A2MAPT | |
| SCHEMBL12168148 | 0.73 | HCAR2 (0.59) | MAPK1HCAR2 | |
| SCHEMBL569002 | 0.72 | — | — | |
| SCHEMBL13279353 | 0.72 | MAPK1 (0.47) | MAPK1LMNAHCAR2 | |
| SCHEMBL17641610 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026481-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |