Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6142283 | 1.00 | FAAH (0.43) | FAAHCES1CNR2TRPV1CNR1 | |
| SCHEMBL6142280 | 0.81 | FAAH (0.44) | FAAHCES1CNR2TRPV1CNR1 | |
| SCHEMBL28516851 | 0.79 | FAAH (0.51) | FAAHCES1SOAT1MEN1TP53 | |
| SCHEMBL109910 | 0.79 | FAAH (0.51) | FAAHCES1SOAT1MEN1TP53 | |
| SCHEMBL28405189 | 0.78 | FAAH (0.48) | FAAHCES1SOAT1MEN1TP53 | |
| SCHEMBL313800 | 0.78 | FAAH (0.38) | FAAHCES1MEN1CYP1A2KMT2A | |
| SCHEMBL15758444 | 0.76 | FAAH (0.54) | FAAHCES1SOAT1MEN1TP53 | |
| SCHEMBL28718241 | 0.75 | SLC6A5 (0.47) | FAAHCES1CNR2TRPV1CNR1 | |
| SCHEMBL7764261 | 0.75 | FAAH (0.49) | FAAHCES1SOAT1MEN1TP53 | |
| SCHEMBL30211894 | 0.75 | FAAH (0.50) | FAAHCNR2TRPV1SOAT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1050069-C | Recirculating portion of high internal phase emulsions prepared in continuous process | PROCTER & GAMBLE (US) | 2000-03-08 | — | — | CN | disclosed |
| CN-1175911-A | Recycling of prepared high internal phase emulsions in a continuous process | PROCTER & GAMBLE (US) | 1998-03-11 | — | — | CN | disclosed |
| CN-1175959-A | Foam material for absorbing aqueous fluids made from high internal phase emulsions having very high water to oil ratios | PROCTER & GAMBLE (US) | 1998-03-11 | — | — | CN | disclosed |