Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2730663 | 0.88 | MAPT (0.58) | MAPTMAPK1KDM4ENPC1GLA | |
| SCHEMBL31065089 | 0.77 | MAOB (0.51) | MAPTMAPK1KDM4ENPC1GLA | |
| SCHEMBL17801328 | 0.72 | MAPT (0.63) | MAPTMAPK1KDM4ENPC1GLA | |
| SCHEMBL16652173 | 0.69 | ABL1 (0.44) | MAPTMAPK1KDM4ENPC1GLA | |
| SCHEMBL7719905 | 0.68 | ALOX5 (0.58) | MAPTMAPK1KDM4ENPC1GLA | |
| SCHEMBL8911866 | 0.68 | MAPT (0.58) | MAPTMAPK1KDM4ENPC1GLA | |
| SCHEMBL1122272 | 0.68 | MAOB (0.59) | MAPTMAPK1KDM4ENPC1GLA | |
| Phenidone SCHEMBL9670254 | 0.68 | MAOB (0.59) | MAPTMAPK1KDM4ENPC1GLA | |
| SCHEMBL12716578 | 0.68 | MAPT (0.77) | MAPTMAPK1KDM4ENPC1GLA | |
| SCHEMBL13387644 | 0.68 | ALOX5 (0.43) | MAPTMAPK1KDM4ENPC1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150373978-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER IP GMBH (DE) | 2015-12-31 | — | — | US | disclosed |
| US-9173396-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-11-03 | — | — | US | disclosed |
| US-20150284380-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2015-10-08 | — | — | US | disclosed |
| EP-2914587-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | Bayer CropScience AG (DE) | 2015-09-09 | — | — | EP | disclosed |
| WO-2014067962-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2014-05-08 | — | — | WO | disclosed |
| US-20130261141-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-10-03 | — | — | US | disclosed |
| EP-2630133-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | Bayer Intellectual Property GmbH (DE) | 2013-08-28 | — | — | EP | disclosed |
| WO-2012052412-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2012-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284380-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | DDT, KEAP1, NISCH | MAPT 4113/4885MAPK1 3091/4885KDM4E 661/4885 |
| US-20130261141-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | DDT, ACHE, PTMS | MAPT 4207/4885MAPK1 4276/4885KDM4E 1664/4885 |
| US-20150373978-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | DDT, ACHE, PTMS | MAPT 4207/4885MAPK1 4276/4885KDM4E 1664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.