Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNG | P07510 | 1/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2730663 | 0.80 | MAPT (0.58) | ABL1KDM4ENPC1GLAMAPT | |
| SCHEMBL10417191 | 0.79 | ALOX5 (0.51) | ABL1CHRNB2CHRNA4CYP11B1CYP11B2 | |
| SCHEMBL16659465 | 0.79 | CYP2A6 (0.45) | CHRNB2CHRNA4CYP2A6CYP3A4KDM4E | |
| SCHEMBL2731119 | 0.76 | MAPT (0.73) | CHRNB2CHRNA4KDM4ENPC1GLA | |
| SCHEMBL13387644 | 0.71 | ALOX5 (0.43) | ABL1KDM4ENPC1GLAMAPT | |
| SCHEMBL2732008 | 0.69 | MAPT (0.50) | ABL1KDM4ENPC1GLAMAPT | |
| SCHEMBL16906435 | 0.69 | CYP11B2 (0.45) | CHRNB2CHRNA4CYP11B1CYP11B2CHRNB4 | |
| SCHEMBL27681500 | 0.69 | MAPT (0.73) | CYP2A6CYP3A4KDM4ENPC1GLA | |
| SCHEMBL30720445 | 0.68 | CHRNB2 (0.45) | CHRNB2CHRNA4CYP2A6CYP3A4MAPT | |
| SCHEMBL29366505 | 0.67 | CYP2A6 (0.44) | CHRNB2CHRNA4CYP2A6CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170101392-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2017-04-13 | — | — | US | claimed |
| US-20160272615-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DOW AGROSCIENCES LLC | 2016-09-22 | — | — | US | claimed |
| EP-3057429-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | Dow AgroSciences LLC (US) | 2016-08-24 | — | — | EP | claimed |
| US-20150250177-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DOW AGROSCIENCES LLC | 2015-09-10 | — | — | US | claimed |
| US-9108946-B2 | Processes for the preparation of pesticidal compounds | DOW AGROSCIENCES LLC (US) | 2015-08-18 | — | — | US | claimed |
| US-20150112078-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DOW AGROSCIENCES LLC | 2015-04-23 | — | — | US | claimed |
| WO-2015058021-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2015-04-23 | — | — | WO | claimed |
| CN-116940560-A | Process for producing 3-bromo-1- (3-chloropyridin-2-yl) -1H-pyrazole-5-carboxylic acid ester | 石原产业株式会社 | 2023-10-24 | — | — | CN | disclosed |
| WO-2022191139-A1 | METHOD FOR PRODUCING 3-BROMO-1-(3-CHLOROPYRIDIN-2-YL)-1H-PYRAZOLE-5-CARBOXYLIC ACID ESTER | 石原産業株式会社 | 2022-09-15 | — | — | WO | disclosed |
| US-20180044319-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2018-02-15 | — | — | US | disclosed |
| US-20180044319-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2018-02-15 | — | — | US | disclosed |
| US-20180044319-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2018-02-15 | — | — | US | disclosed |
| US-20170101392-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2017-04-13 | — | — | US | disclosed |
| US-9108946-B2 | Processes for the preparation of pesticidal compounds | DOW AGROSCIENCES LLC (US) | 2015-08-18 | — | — | US | disclosed |
| US-9108946-B2 | Processes for the preparation of pesticidal compounds | DOW AGROSCIENCES LLC (US) | 2015-08-18 | — | — | US | disclosed |
| WO-2015058021-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2015-04-23 | — | — | WO | disclosed |
| US-20150112078-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DOW AGROSCIENCES LLC | 2015-04-23 | — | — | US | disclosed |
| US-20150112078-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DOW AGROSCIENCES LLC | 2015-04-23 | — | — | US | disclosed |
| US-20150112078-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DOW AGROSCIENCES LLC | 2015-04-23 | — | — | US | disclosed |
| WO-2015058021-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2015-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150112078-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DDT, ACHE, PTMS | ABL1 3840/4885CHRNB2 1722/4885CHRNA4 2441/4885 |
| US-20180044319-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DDT, ACHE, PTMS | ABL1 3840/4885CHRNB2 1722/4885CHRNA4 2441/4885 |
| US-20170101392-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DDT, ACHE, PTMS | ABL1 3840/4885CHRNB2 1722/4885CHRNA4 2441/4885 |
| US-20160272615-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DDT, ACHE, PTMS | ABL1 3840/4885CHRNB2 1722/4885CHRNA4 2441/4885 |
| US-20150250177-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DDT, ACHE, PTMS | ABL1 3840/4885CHRNB2 1722/4885CHRNA4 2441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.