Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970855 | 0.73 | NPC1 (0.52) | ADORA2BPOLBTDP1MAPTKMT2A | |
| SCHEMBL23495094 | 0.71 | CHRM2 (0.43) | TDP1ALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL12648261 | 0.69 | POLB (0.54) | ADORA2BPOLBTDP1MAPTKMT2A | |
| SCHEMBL27915340 | 0.69 | NAAA (0.43) | MAPTKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL6324049 | 0.67 | MMP1 (0.46) | POLBMAPTKMT2ANPSR1ALDH1A1 | |
| SCHEMBL13351529 | 0.66 | MTNR1A (0.47) | MAPTKMT2AALDH1A1TSHRMEN1 | |
| Hydrochloric Acid SCHEMBL27680685 | 0.66 | MMP1 (0.45) | POLBMAPTKMT2ANPSR1ALDH1A1 | |
| SCHEMBL8367646 | 0.66 | CHRM2 (0.40) | ALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL28259375 | 0.66 | CHRM2 (0.40) | ALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL7970858 | 0.66 | ADORA2B (0.42) | ADORA2BPOLBTDP1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1029230-C | Hydroxamic acid and N-hydroxyurea derivatives and their use | PFIZER (US) | 1995-07-05 | — | — | CN | disclosed |
| CN-1061775-A | New hydroxamic acid and N-hydroxyl urea derivant and uses thereof | PFIZER (US) | 1992-06-10 | — | — | CN | disclosed |