Benzophenone

Benzophenone

SCHEMBL27323738

C=CCC(=O)O.O=C(c1ccccc1)c1ccccc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.58
LMNA P02545 3/20 0.56
HPGD P15428 3/20 0.56
ATM Q13315 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
SRD5A2 P31213 1/20 0.50
AKT1 P31749 1/20 0.48
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
AKR1B1 P15121 1/20 0.46
MAPT P10636 2/20 0.44
ALOX12 P18054 1/20 0.44
RECQL P46063 1/20 0.44
RAB9A P51151 2/20 0.44
PAM P19021 1/20 0.44
MAPK13 O15264 1/20 0.44
MAPK12 P53778 1/20 0.44
MAPK11 Q15759 1/20 0.44
MAPK14 Q16539 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL11147183 0.88 TSHR (0.58) ALDH1A1LMNAHPGDTDP1L3MBTL1
Benzophenone SCHEMBL18171700 0.86 ALDH1A1 (0.56) ALDH1A1LMNAHPGDATMTDP1
Biphenyl SCHEMBL11045970 0.83 LMNA (0.48) ALDH1A1LMNAHPGDL3MBTL1AKT1
SCHEMBL28194542 0.82 AKT1 (0.44) ALDH1A1LMNAHPGDATMTDP1
Benzene SCHEMBL11645295 0.82 ALDH1A1 (0.47) ALDH1A1LMNAHPGDAKT1MEN1
Benzophenone SCHEMBL5566782 0.81 ALDH1A1 (0.61) ALDH1A1LMNAHPGDATMTDP1
Phenol SCHEMBL17183829 0.81 CA2 (0.48) ALDH1A1TDP1AKT1AKR1B1PAM
Benzophenone SCHEMBL5056577 0.79 ALDH1A1 (0.58) ALDH1A1LMNAHPGDATMTDP1
SCHEMBL10781610 0.79 PAM (0.44) ALDH1A1LMNAHPGDTDP1AKT1
O-Xylene SCHEMBL4088288 0.79 PAM (0.44) ALDH1A1L3MBTL1AKT1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101242807-B Mouth-moistening compositions, delivery systems comprising the same, and methods of making the same KRAFT FOODS GLOBAL BRANDS LLC 2014-12-10 CN claimed
CN-101242807-A Mouth-moistening compositions, delivery systems comprising the same, and methods of making the same CADBURY ADAMS USA LLC (US) 2008-08-13 CN claimed
CN-101242807-B Mouth-moistening compositions, delivery systems comprising the same, and methods of making the same KRAFT FOODS GLOBAL BRANDS LLC 2014-12-10 CN disclosed
CN-101242807-A Mouth-moistening compositions, delivery systems comprising the same, and methods of making the same CADBURY ADAMS USA LLC (US) 2008-08-13 CN disclosed
CN-1049776-A IMPROVED SALT SUBSTITUTE GRANULE WARNER LAMBERT CO (US) 1991-03-13 CN disclosed