Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.78 |
| ▸ | MAOB | P27338 | 9/20 | 0.72 |
| ▸ | MAOA | P21397 | 8/20 | 0.72 |
| ▸ | PRKCI | P41743 | 1/20 | 0.72 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29983572 | 1.00 | PBRM1 (0.78) | PBRM1MAOBMAOAPRKCIHSD17B1 | |
| Hydrochloric Acid SCHEMBL6531236 | 0.96 | PBRM1 (0.72) | PBRM1MAOBMAOAPRKCIHSD17B1 | |
| SCHEMBL5145478 | 0.96 | PBRM1 (0.78) | PBRM1MAOBMAOAPRKCIHSD17B1 | |
| SCHEMBL28880 | 0.88 | PBRM1 (1.00) | PBRM1MAOBMAOAPRKCIHSD17B1 | |
| SCHEMBL30137886 | 0.88 | PBRM1 (1.00) | PBRM1MAOBMAOAPRKCIHSD17B1 | |
| SCHEMBL228128 | 0.84 | MAOA (1.00) | PBRM1MAOBMAOAPRKCIHSD17B1 | |
| SCHEMBL3825921 | 0.80 | MAOA (0.92) | PBRM1MAOBMAOAPRKCIHSD17B1 | |
| SCHEMBL29483386 | 0.80 | MAOA (0.53) | PBRM1MAOBMAOAPRKCIHSD17B1 | |
| SCHEMBL355820 | 0.80 | MAOA (0.53) | PBRM1MAOBMAOAPRKCIHSD17B1 | |
| SCHEMBL27323917 | 0.79 | MAOB (0.77) | PBRM1MAOBMAOAPRKCIHSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 502 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108928-B | Nitrogen mustard-tetralone derivative, preparation method and application thereof | 广东海洋大学 | 2024-06-11 | — | — | CN | claimed |
| CN-211384964-U | Cooling device of reaction kettle for producing and preparing 7-hydroxy-1-tetralone | 武汉海昕药物研究有限公司 | 2020-09-01 | — | — | CN | claimed |
| CN-106977377-B | Preparation method of 7-hydroxy-1-tetralone | 江西同和药业股份有限公司 | 2020-06-30 | — | — | CN | claimed |
| CN-109265431-B | Synthesis process of 3-acetyl-10, 11-dihydro-5H-dibenzo [ C, G ] chromen-8 (9H) -one | 江苏苏利精细化工股份有限公司 | 2020-05-26 | — | — | CN | claimed |
| CN-109265431-A | 3- acetyl group -10,11- dihydro -5H- dibenzo [C, G] chromene -8(9H) -one synthesis technology | 江苏苏利精细化工股份有限公司 | 2019-01-25 | — | — | CN | claimed |
| CN-108794316-A | Preparation process of 7-hydroxy-3, 4-dihydro-2H-1-naphthalenone | 海门市新港医药科技有限公司 | 2018-11-13 | — | — | CN | claimed |
| EP-2909166-A1 | PROCESSES FOR THE PREPARATION OF AGOMELATINE USING NOVEL INTERMEDIATES | Symed Labs Limited (IN) | 2015-08-26 | — | — | EP | claimed |
| WO-2014064706-A1 | PROCESSES FOR THE PREPARATION OF AGOMELATINE USING NOVEL INTERMEDIATES | SYMED LABS LIMITED (IN) | 2014-05-01 | — | — | WO | claimed |
| EP-2194035-B1 | Hydroxytetralones | SALTIGO GMBH (DE) | 2011-11-02 | — | — | EP | claimed |
| EP-2194035-A2 | Hydroxytetralones | Saltigo GmbH (DE) | 2010-06-09 | — | — | EP | claimed |
| CN-122074043-A | Combination therapy with KRAS modulators | 光达治疗公司 | 2026-05-22 | — | — | CN | disclosed |
| CN-122059824-A | Synthesis method of ilalastyl chiral intermediate | 上海格苓凯生物科技有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-118026958-B | 3, 4-Dihydro-1 (2H) -naphthalenone derivative, preparation method and application thereof | 滨州医学院 | 2026-05-12 | — | — | CN | disclosed |
| US-12624052-B2 | KRAS modulators and uses thereof | QUANTA THERAPEUTICS, INC. (US) | 2026-05-12 | — | — | US | disclosed |
| US-12509417-B2 | Enantioselective process | SYNGENTA CROP PROTECTION AG (CH) | 2025-12-30 | — | — | US | disclosed |
| US-4001301-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS, ANTI-PRURITIC | SYNTEX CORPORATION (PM) | 1977-01-04 | — | — | US | disclosed |
| US-3998966-A | Anti-inflammatory, analgesic, anti-pyretic and anti-pruritic 6-substituted 2-naphthyl acetic acid derivative-containing compositions and methods of use thereof | SYNTEX CORPORATION (PM) | 1976-12-21 | — | — | US | disclosed |
| US-3980699-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETIC, ANTIPRURITIC | SYNTEX CORPORATION (PM) | 1976-09-14 | — | — | US | disclosed |
| US-3978116-A | ANALGESIC, ANTIPYRETIC | SYNTEX CORPORATION (PM) | 1976-08-31 | — | — | US | disclosed |
| US-3978124-A | ANALGESIC, ANTIPYRETIC | SYNTEX CORPORATION (PM) | 1976-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12509417-B2 | Enantioselective process | HCCS, AOC3, CYP8B1 | PBRM1 1854/4885MAOB 278/4885MAOA 354/4885 |
| US-12624052-B2 | KRAS modulators and uses thereof | KRAS, NRAS, HRAS | PBRM1 367/4885MAOB 4747/4885MAOA 4851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.