Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27327257 | 0.89 | S1PR4 (0.48) | S1PR4ALDH1A1RAB9AMAPTS1PR2 | |
| SCHEMBL27327663 | 0.89 | S1PR4 (0.53) | S1PR4ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL27327664 | 0.89 | S1PR4 (0.53) | S1PR4MAPTS1PR2MEN1KMT2A | |
| SCHEMBL27327484 | 0.88 | LMNA (0.43) | S1PR4ALDH1A1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL27327477 | 0.88 | ALDH1A1 (0.39) | S1PR4ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27327670 | 0.85 | HTR6 (0.47) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL27327672 | 0.85 | ALDH1A1 (0.45) | ALDH1A1NPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL27327653 | 0.85 | POLB (0.41) | S1PR4ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL27327476 | 0.84 | AGER (0.39) | S1PR4ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27327483 | 0.83 | FTO (0.43) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024103400-A1 | POLYCYCLIC COMPOUND AS GPR75 ACTIVATOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 水木未来(北京)科技有限公司 | 2024-05-23 | — | — | WO | disclosed |