Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2723233 | 0.92 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1LMNAGLAMEN1 | |
| SCHEMBL17788090 | 0.85 | ALKBH2 (0.40) | ALDH1A1L3MBTL1LMNAGLAMEN1 | |
| SCHEMBL16385359 | 0.85 | ADORA2A (0.34) | ALDH1A1LMNATDP1MAPTPIK3CD | |
| SCHEMBL6403237 | 0.74 | PTGS2 (0.52) | KDM4EALKBH2ALKBH5FTO | |
| SCHEMBL6404681 | 0.72 | PTGS2 (0.50) | HPGDALKBH2ALKBH5ALKBH3FTO | |
| SCHEMBL22428154 | 0.72 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1LMNAGLAMCL1 | |
| SCHEMBL2680314 | 0.71 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1LMNAGLAMEN1 | |
| SCHEMBL22427968 | 0.71 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1LMNAGLAMEN1 | |
| SCHEMBL2681649 | 0.71 | ALDH1A1 (0.43) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL2680256 | 0.70 | SMN1; SMN2 (0.40) | ALDH1A1L3MBTL1LMNAGLAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2629614-B1 | NEMATOCIDAL SULFONAMIDES | DU PONT (US) | 2014-09-17 | — | — | EP | claimed |
| US-20130190172-A1 | NEMATOCIDAL SULFONAMIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-07-25 | — | — | US | claimed |
| EP-3020715-B1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2021-06-16 | — | — | EP | disclosed |
| EP-3020715-B1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2021-06-16 | — | — | EP | disclosed |
| EP-3029030-B1 | TETRAZOLINONE COMPOUND, AND USE THEREFOR | SUMITOMO CHEMICAL CO (JP) | 2019-09-04 | — | — | EP | disclosed |
| EP-3029038-B1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2019-03-27 | — | — | EP | disclosed |
| EP-3029038-B1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2019-03-27 | — | — | EP | disclosed |
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |
| US-9888688-B2 | Tetrazolinone compounds and applications thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-02-13 | — | — | US | disclosed |
| US-9888688-B2 | Tetrazolinone compounds and applications thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-02-13 | — | — | US | disclosed |
| US-9781933-B2 | Tetrazolinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-10-10 | — | — | US | disclosed |
| EP-3020715-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | Sumitomo Chemical Company Limited (JP) | 2016-05-18 | — | — | EP | disclosed |
| US-9023850-B2 | Nematocidal sulfonamides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-05-05 | — | — | US | disclosed |
| WO-2015016335-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | 住友化学株式会社 (JP) | 2015-02-05 | — | — | WO | disclosed |
| WO-2015016335-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | 住友化学株式会社 (JP) | 2015-02-05 | — | — | WO | disclosed |
| WO-2015005499-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | 住友化学株式会社 (JP) | 2015-01-15 | — | — | WO | disclosed |
| EP-2629614-B1 | NEMATOCIDAL SULFONAMIDES | DU PONT (US) | 2014-09-17 | — | — | EP | disclosed |
| EP-2629614-A1 | NEMATOCIDAL SULFONAMIDES | E.I. Du Pont De Nemours And Company (US) | 2013-08-28 | — | — | EP | disclosed |
| US-20130190172-A1 | NEMATOCIDAL SULFONAMIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-07-25 | — | — | US | disclosed |
| WO-2012054233-A1 | NEMATOCIDAL SULFONAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190172-A1 | NEMATOCIDAL SULFONAMIDES | QSOX1, ARSA, NOX1 | ALDH1A1 703/4885L3MBTL1 723/4885LMNA 3746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.