Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | FLT1 | P17948 | 2/20 | 0.32 |
| ▸ | FLT4 | P35916 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17788090 | 0.85 | ALKBH2 (0.40) | ADORA2AADORA1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL2732971 | 0.85 | ALDH1A1 (0.42) | PIK3CDPIK3CAPIK3CBPIK3CGFLT1 | |
| SCHEMBL2723233 | 0.77 | ALDH1A1 (0.45) | PIK3CDPIK3CAPIK3CBPIK3CGFLT1 | |
| SCHEMBL6403237 | 0.74 | PTGS2 (0.52) | PTGS2PTGS1EGFR | |
| SCHEMBL16402989 | 0.68 | NPC1 (0.40) | PIK3CDPIK3CAPIK3CBPIK3CGTDP1 | |
| SCHEMBL16403402 | 0.68 | NPC1 (0.40) | PIK3CDPIK3CAPIK3CBPIK3CGTDP1 | |
| SCHEMBL2680302 | 0.67 | NPC1 (0.39) | PIK3CDPIK3CAPIK3CBPIK3CGTDP1 | |
| SCHEMBL15946212 | 0.66 | ALKBH2 (0.41) | PTGS2FLT1FLT4KDRPOLB | |
| SCHEMBL3499989 | 0.64 | RXFP1 (0.50) | ADORA2AADORA1PTGS2POLBPTGS1 | |
| SCHEMBL21317158 | 0.64 | FLT1 (0.41) | PTGS2FLT1FLT4KDRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160174558-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-06-23 | — | — | US | disclosed |
| WO-2015005499-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | 住友化学株式会社 (JP) | 2015-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160174558-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | MT-CO1, KCNA5, MT-CO2 | ADORA2A 3432/4885ADORA1 1586/4885PIK3CD 2943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.