SCHEMBL2733181

SCHEMBL2733181

COCCCNCC(N)=O

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.53
MAOB P27338 2/20 0.53
TSHR P16473 2/20 0.47
ALDH1A1 P00352 7/20 0.44
RECQL P46063 1/20 0.42
KDM4E B2RXH2 8/20 0.40
GAA P10253 2/20 0.39
LMNA P02545 3/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
EPHX2 P34913 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
MEN1 O00255 1/20 0.37
NPC1 O15118 1/20 0.37
KMT2A Q03164 1/20 0.37
USP2 O75604 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7085337 0.94 MAOA (0.57) MAOAMAOBTSHRALDH1A1RECQL
SCHEMBL2472523 0.87
SCHEMBL11337099 0.82 TSHR (0.50) TSHRALDH1A1RECQLKDM4EGAA
SCHEMBL7899608 0.81 TSHR (0.48) TSHRALDH1A1RECQLKDM4EGAA
SCHEMBL601344 0.81 ALDH1A1 (0.54) TSHRALDH1A1RECQLKDM4EGAA
SCHEMBL15929955 0.81 TSHR (0.48) TSHRALDH1A1RECQLKDM4EGAA
SCHEMBL8337374 0.80 MAOA (0.41) MAOAMAOBTSHRALDH1A1RECQL
SCHEMBL28069490 0.79 TSHR (0.47) TSHRALDH1A1RECQLKDM4EGAA
Ammonia Solution, Strong SCHEMBL27509242 0.79 ALDH1A1 (0.52) TSHRALDH1A1RECQLKDM4EGAA
SCHEMBL13793742 0.78 TSHR (0.50) TSHRALDH1A1RECQLKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9878484-B2 Horizontal intermittent motion thermoforming machine RECKITT BENCKISER (UK) LIMITED (GB) 2018-01-30 US disclosed
US-9650739-B2 Gradual-release dosing device and seal of a domestic-use apparatus RECKITT BENCKISER CALGON B.V. (NL) 2017-05-16 US disclosed
US-20140154350-A1 Process and Mould for Thermoforming Containers RECKITT BENCKISER (UK) LIMITED (GB) 2014-06-05 US disclosed
US-20130243661-A1 Gradual-Release Dosing Device and Seal of a Domestic-Use Apparatus RECKITT BENCKISER CALGON B.V. (NL) 2013-09-19 US disclosed
US-20110062308-A1 PROCESS AND MOULD FOR THERMOFORMING CONTAINERS RECKITT BENCKISER (UK) LIMITED (GB) 2011-03-17 US disclosed
US-20080136055-A1 Cleaning Tablets or Water-Softening Tablets and their Manufacture RECKITT BENCKISER (UK) LIMITED (GB) 2008-06-12 US disclosed
US-20060293447-A1 Water soluble package and for producing it RECKITT BENCKISER N.V. (NL) 2006-12-28 US disclosed
US-20060230709-A1 Method for producing a water soluble package RECKITT BENCKISER (UK) LIMITED (GB) 2006-10-19 US disclosed
US-20050181963-A1 Stain treating composition RECKITT BENCKISER N.V. (NL) 2005-08-18 US disclosed
US-20040118738-A1 Water-soluble container having at least two openings RECKITT BENCKISER (UK) LIMITED (GB) 2004-06-24 US disclosed