Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2472523 | 0.88 | — | — | |
| SCHEMBL31662674 | 0.83 | MAOA (0.40) | MAOAMAOBALDH1A1TSHRKDM4E | |
| SCHEMBL26292904 | 0.82 | ALDH1A1 (0.40) | ALDH1A1TSHRCA2ATMKDM4E | |
| SCHEMBL2125093 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TSHRCA2ATMKDM4E | |
| SCHEMBL20535410 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TSHRCA2ATMKDM4E | |
| SCHEMBL29626483 | 0.81 | MEN1 (0.42) | ALDH1A1TSHRKDM4ERECQLMEN1 | |
| SCHEMBL2733181 | 0.80 | MAOA (0.53) | MAOAMAOBALDH1A1TSHRKDM4E | |
| SCHEMBL8333250 | 0.80 | MAOA (0.44) | MAOAMAOBALDH1A1TSHRKDM4E | |
| SCHEMBL7365096 | 0.79 | PAOX (0.42) | MAOAMAOBALDH1A1TSHRKDM4E | |
| SCHEMBL7085337 | 0.78 | MAOA (0.57) | MAOAMAOBALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043953-A1 | PYRIMIDINE COMPOUNDS | CYCLACEL LIMITED (GB) | 2004-05-27 | — | — | WO | disclosed |