Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27509242 | 0.98 | ALDH1A1 (0.52) | ALDH1A1TSHRKDM4ERECQLLMNA | |
| SCHEMBL29358384 | 0.90 | ALDH1A1 (0.53) | ALDH1A1TSHRKDM4ELMNAL3MBTL1 | |
| SCHEMBL157970 | 0.86 | — | — | |
| SCHEMBL7899608 | 0.83 | TSHR (0.48) | ALDH1A1TSHRKDM4ERECQLLMNA | |
| SCHEMBL15929955 | 0.83 | TSHR (0.48) | ALDH1A1TSHRKDM4ERECQLLMNA | |
| SCHEMBL19668597 | 0.81 | EPHX1 (0.46) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| SCHEMBL2733181 | 0.81 | MAOA (0.53) | ALDH1A1TSHRKDM4ERECQLLMNA | |
| SCHEMBL28069490 | 0.81 | TSHR (0.47) | ALDH1A1TSHRKDM4ERECQLLMNA | |
| SCHEMBL13793742 | 0.79 | TSHR (0.50) | ALDH1A1TSHRKDM4ERECQLLMNA | |
| SCHEMBL20535410 | 0.79 | ALDH1A1 (0.41) | ALDH1A1TSHRKDM4ERECQLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | claimed |
| EP-0656349-B1 | Amidinophenol derivatives having phospholipase A2 inhibitory activity | ONO PHARMACEUTICAL CO (JP) | 1998-04-08 | — | — | EP | claimed |
| US-12281180-B2 | Peptoid-peptide macrocycles, pharmaceutical compositions and methods of using the same | NEW YORK UNIVERSITY (US) | 2025-04-22 | — | — | US | disclosed |
| WO-2025070720-A1 | PEPTIDE | ペプチドリーム株式会社 | 2025-04-03 | — | — | WO | disclosed |
| WO-2025070731-A1 | PEPTIDEPEPTIDE | ペプチドリーム株式会社 | 2025-04-03 | — | — | WO | disclosed |
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | disclosed |
| US-20240287138-A1 | CYCLIC PEPTIDES FOR INHIBITING TNF RECEPTOR 1 ACTIVITY | MERCK SHARP & DOHME LLC | 2024-08-29 | — | — | US | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-20120040904-A1 | Boronate Medicaments for Preventing Thrombosis During Surgery | Trigen Holdings AG (GB) | 2012-02-16 | — | — | US | disclosed |
| US-20100113393-A1 | Boronic Acid Salts | PAION DEUTSCHLAND GMBH (DE) | 2010-05-06 | — | — | US | disclosed |
| US-20100035827-A1 | Multivalent metal salts of boronic acids | PAION DEUTSCHLAND GMBH (DE) | 2010-02-11 | — | — | US | disclosed |
| EP-0807638-A1 | Inhibitors and substrates of thrombin | THROMBOSIS RESEARCH INSTITUTE (GB) | 1997-11-19 | — | — | EP | disclosed |
| US-5648338-A | PEPTIDE ANTICOAGULANT | THROMBOSIS RESEARCH INSTITUTE (GB) | 1997-07-15 | — | — | US | disclosed |
| US-5639739-A | USEFUL FOR TREATING THROMBOSIS IN MAMMALS BY INHIBITING TRYPSIN-LIKE SERINE PROTEASE ENZYMES | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-06-17 | — | — | US | disclosed |
| US-5563127-A | USEFUL TO TREAT THROMBOSIS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| WO-1996025427-A1 | SERINE PROTEASE INHIBITORS | ELLERMAN PHARMACEUTICALS LIMITED (GB) | 1996-08-22 | — | — | WO | disclosed |
| WO-1996020689-A2 | BORONIC ACID AND ESTER INHIBITORS OF THROMBIN | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-07-11 | — | — | WO | disclosed |
| WO-1994021650-A1 | BORONIC ACID AND ESTER INHIBITORS OF THROMBIN | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-09-29 | — | — | WO | disclosed |
| EP-0509080-A1 | INHIBITORS AND SUBSTRATES OF THROMBIN | ELLERMAN PHARMACEUTICALS LIMITED (GB) | 1992-10-21 | — | — | EP | disclosed |
| WO-1992007869-A1 | INHIBITORS AND SUBSTRATES OF THROMBIN | THROMBOSIS RESEARCH INSTITUTE (GB) | 1992-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040904-A1 | Boronate Medicaments for Preventing Thrombosis During Surgery | F9, FGB, TFPI | ALDH1A1 3387/4885TSHR 282/4885KDM4E 3829/4885 |
| US-20100113393-A1 | Boronic Acid Salts | GCG, GRPR, BPGM | ALDH1A1 4864/4885TSHR 485/4885KDM4E 4277/4885 |
| US-20100035827-A1 | Multivalent metal salts of boronic acids | BTD, SLC5A6, BPGM | ALDH1A1 4767/4885TSHR 3151/4885KDM4E 4677/4885 |
| US-20240287138-A1 | CYCLIC PEPTIDES FOR INHIBITING TNF RECEPTOR 1 ACTIVITY | TNF, TNFRSF1A, CD40 | ALDH1A1 3774/4885TSHR 708/4885KDM4E 3704/4885 |
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | BCAT1, BCAT2, PELP1 | ALDH1A1 4472/4885TSHR 2791/4885KDM4E 3586/4885 |
| US-12281180-B2 | Peptoid-peptide macrocycles, pharmaceutical compositions and methods of using the same | WNT1, WNT3, WNT3A | ALDH1A1 4878/4885TSHR 3550/4885KDM4E 4720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.