Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2733181 | 0.94 | MAOA (0.53) | MAOAMAOBTSHRALDH1A1KDM4E | |
| SCHEMBL2472523 | 0.85 | — | — | |
| SCHEMBL13033160 | 0.82 | TSHR (0.42) | TSHRALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL29358384 | 0.78 | ALDH1A1 (0.53) | TSHRALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL8337374 | 0.78 | MAOA (0.41) | MAOAMAOBTSHRALDH1A1KDM4E | |
| Milacemide SCHEMBL194513 | 0.77 | MAOA (0.63) | MAOAMAOBTSHRALDH1A1GAA | |
| SCHEMBL11337099 | 0.76 | TSHR (0.50) | TSHRALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL7338476 | 0.75 | MAOA (0.67) | MAOAMAOBTSHRALDH1A1KMT2A | |
| SCHEMBL7340676 | 0.75 | MAOA (0.67) | MAOAMAOBTSHRALDH1A1KMT2A | |
| SCHEMBL19745716 | 0.75 | MAOA (0.67) | MAOAMAOBTSHRALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1284961-A1 | GLYCINAMIDES | MERCK PATENT GmbH (DE) | 2003-02-26 | — | — | EP | disclosed |
| WO-2001092219-A1 | GLYCINAMIDES | MERCK PATENT GMBH (DE) | 2001-12-06 | — | — | WO | disclosed |