SCHEMBL2733767

SCHEMBL2733767

c1ccc(-c2cc(-c3cncc4ccccc34)c(-c3ccccc3)c3c2-c2cccc4cccc-3c24)cc1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PRKCZ Q05513 1/20 0.48
CYP17A1 P05093 3/20 0.43
CYP11B1 P15538 12/20 0.41
CYP11B2 P19099 12/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2D6 P10635 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2B6 P20813 2/20 0.41
CYP2C19 P33261 2/20 0.41
CYP1A2 P05177 1/20 0.41
TNF P01375 1/20 0.39
KCNA5 P22460 1/20 0.38
KCNH2 Q12809 1/20 0.38
ERN1 O75460 2/20 0.38
MMP1 P03956 1/20 0.37
MMP9 P14780 1/20 0.37
SERPINE1 P05121 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2140937 0.86 ALDH1A1 (0.40) TNF
SCHEMBL2158220 0.83 ALDH1A1 (0.47) CYP3A4TNF
SCHEMBL2734539 0.82 CYP11B1 (0.49) CYP17A1CYP11B1CYP11B2CYP3A4CYP2C9
SCHEMBL2734065 0.82 ATM (0.43) CYP11B1CYP11B2TNFKCNA5KCNH2
SCHEMBL2734772 0.82 TNF (0.44) PRKCZCYP17A1CYP11B1CYP11B2CYP3A4
SCHEMBL12202470 0.82 PRKCZ (0.44) PRKCZCYP17A1CYP11B1CYP11B2CYP3A4
SCHEMBL22955971 0.81 PRKCZ (0.50) PRKCZCYP17A1CYP11B1CYP11B2CYP3A4
SCHEMBL2734566 0.80 TNF (0.45) PRKCZTNF
SCHEMBL76389 0.80 ALDH1A1 (0.44) CYP3A4TNF
SCHEMBL16859291 0.80 ALDH1A1 (0.44) CYP3A4TNF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088500-B2 OLED device with fluoranthene electron injection materials GLOBAL OLED TECHNOLOGY LLC (US) 2012-01-03 US disclosed
US-8088500-B2 OLED device with fluoranthene electron injection materials GLOBAL OLED TECHNOLOGY LLC (US) 2012-01-03 US disclosed
US-20100117520-A1 OLED DEVICE WITH FLUORANTHENE ELECTRON INJECTION MATERIALS GLOBAL OLED TECHNOLOGY LLC 2010-05-13 US disclosed
US-20100117520-A1 OLED DEVICE WITH FLUORANTHENE ELECTRON INJECTION MATERIALS GLOBAL OLED TECHNOLOGY LLC 2010-05-13 US disclosed