Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7450375 | 0.91 | FFAR1 (0.39) | FFAR1CYP26A1MAPTLMNAPOLB | |
| SCHEMBL7450364 | 0.89 | MAPT (0.43) | FFAR1MAPTLMNAPOLBMAPK1 | |
| SCHEMBL9785916 | 0.84 | MEN1 (0.53) | MEN1KMT2AMMP8 | |
| SCHEMBL2483684 | 0.79 | LMNA (0.45) | MAPTLMNAPOLBMAPK1MEN1 | |
| SCHEMBL13240785 | 0.79 | LMNA (0.45) | MAPTLMNAPOLBMAPK1MEN1 | |
| SCHEMBL15645799 | 0.78 | MMP8 (0.50) | MAPTLMNAPOLBMEN1CYP2D6 | |
| SCHEMBL5685475 | 0.77 | MAPT (0.55) | FFAR1MAPTLMNAPOLBMAPK1 | |
| SCHEMBL17724447 | 0.77 | CES2 (0.55) | FFAR1MAPTLMNAPOLBMEN1 | |
| SCHEMBL13194421 | 0.77 | LMNA (0.46) | MAPTLMNAPOLBMEN1CYP2D6 | |
| SCHEMBL17825651 | 0.76 | ROCK2 (0.45) | MAPTLMNAMEN1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1041720-C | Bicyclic amide derivatives, preparation method thereof, pharmaceutical composition and pharmaceutical application thereof | WELLCOME FOUND (GB) | 1999-01-20 | — | — | CN | disclosed |
| CN-1125938-A | Bicyclic amide derivatives and their use as muscle relaxants | WELLCOME FOUND (GB) | 1996-07-03 | — | — | CN | disclosed |