Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 7/20 | 0.46 |
| ▸ | WNT3A | P56704 | 7/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27364321 | 0.81 | CTNNB1 (0.43) | CTNNB1WNT3AKEAP1NFE2L2CLK1 | |
| SCHEMBL27629579 | 0.74 | CTNNB1 (0.68) | CTNNB1WNT3AATMTAS1R3TAS1R1 | |
| SCHEMBL4848144 | 0.71 | CTNNB1 (0.56) | CTNNB1WNT3ACLK1TAS1R3TAS1R1 | |
| SCHEMBL10693468 | 0.71 | CTNNB1 (0.47) | CTNNB1WNT3AKEAP1NFE2L2CLK1 | |
| SCHEMBL9535006 | 0.70 | CTNNB1 (0.46) | CTNNB1WNT3AKEAP1NFE2L2NPC1 | |
| SCHEMBL8805389 | 0.70 | CTNNB1 (0.42) | CTNNB1WNT3AKEAP1NFE2L2CLK1 | |
| SCHEMBL25455117 | 0.69 | CTNNB1 (0.48) | CTNNB1WNT3ANPC1RAB9APOLB | |
| SCHEMBL11242424 | 0.69 | CTNNB1 (0.54) | CTNNB1WNT3ACLK1ATMTAS1R3 | |
| SCHEMBL1726294 | 0.69 | CTNNB1 (0.61) | CTNNB1WNT3ACLK1DYRK1ADYRK1B | |
| SCHEMBL3782345 | 0.69 | CTNNB1 (0.57) | CTNNB1WNT3ACLK1DYRK1ADYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1060286-A | Antiinflammatory hydroxamic acids and N-hydroxyurea | PFIZER (US) | 1992-04-15 | — | — | CN | disclosed |