Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 7/20 | 0.43 |
| ▸ | WNT3A | P56704 | 7/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | PIR | O00625 | 1/20 | 0.38 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27342125 | 0.81 | CTNNB1 (0.46) | CTNNB1WNT3ACLK1DYRK1ADYRK1B | |
| SCHEMBL9206920 | 0.80 | RXRA (0.48) | — | |
| SCHEMBL1726294 | 0.69 | CTNNB1 (0.61) | CTNNB1WNT3ACLK1DYRK1ADYRK1B | |
| SCHEMBL3782345 | 0.69 | CTNNB1 (0.57) | CTNNB1WNT3ACLK1DYRK1ADYRK1B | |
| SCHEMBL29739444 | 0.69 | CYP1A2 (0.65) | CTNNB1WNT3APIRHSF1 | |
| SCHEMBL2245406 | 0.69 | CYP1A2 (0.65) | CTNNB1WNT3APIRHSF1 | |
| SCHEMBL671055 | 0.69 | CTNNB1 (0.57) | CTNNB1WNT3APIRHSF1PRKCI | |
| SCHEMBL23432653 | 0.68 | TRIM24 (0.44) | CTNNB1WNT3ACLK1DYRK1ADYRK1B | |
| SCHEMBL29546196 | 0.68 | TRIM24 (0.44) | CTNNB1WNT3ACLK1DYRK1ADYRK1B | |
| SCHEMBL27363199 | 0.68 | ACHE (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1060286-A | Antiinflammatory hydroxamic acids and N-hydroxyurea | PFIZER (US) | 1992-04-15 | — | — | CN | disclosed |