SCHEMBL27344293

SCHEMBL27344293

O=Cc1ccc2c(c1)Oc1ccccc1N2

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 9/20 0.59
HTR2B P41595 2/20 0.47
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
KIF11 P52732 2/20 0.41
ALDH1A1 P00352 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
HSD17B10 Q99714 1/20 0.41
HTR7 P34969 1/20 0.40
MAPT P10636 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
POLB P06746 1/20 0.38
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30811568 1.00 ALOX5 (0.59) ALOX5HTR2BMEN1KMT2AKIF11
SCHEMBL27344294 0.91 ALDH1A1 (0.47) ALOX5HTR2BKIF11ALDH1A1TDP1
SCHEMBL30811558 0.91 ALDH1A1 (0.47) ALOX5HTR2BKIF11ALDH1A1TDP1
SCHEMBL28230706 0.90 ALOX5 (0.64) ALOX5HTR2BMEN1KMT2AKIF11
Benzaldehyde SCHEMBL28774087 0.90 ALDH1A1 (0.48) ALOX5HTR2BMEN1KMT2AKIF11
Phenoxazine SCHEMBL5078606 0.84 ALOX5 (0.65) ALOX5HTR2BMEN1KMT2AALDH1A1
SCHEMBL31512577 0.81 HSD17B10 (0.44) ALOX5ALDH1A1TDP1HSD17B10MAPT
SCHEMBL27716790 0.81 ALDH5A1 (0.44) ALOX5HTR2BMEN1KMT2AALDH1A1
SCHEMBL31512632 0.79 ALOX5 (0.53) ALOX5HTR2BMEN1KMT2AALDH1A1
SCHEMBL31512624 0.79 ALDH1A1 (0.39) ALOX5MEN1KMT2AKIF11ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110301052-A Photo-electric conversion element and optical region sensor, image pick-up element and the image pick up equipment for using it 佳能株式会社 2019-10-01 CN claimed
CN-107556303-A A kind of compound, its synthetic method and utilize kit made of the compound and its application in glutathione detection 潍坊医学院 2018-01-09 CN claimed
CN-107530062-A oral sampling swab and use thereof 宝洁公司 2018-01-02 CN claimed
US-20250326726-A1 FERROPTOSIS INHIBITORS-PHENOXAZINE ACETAMIDES SIRONAX BEIJING CO LTD (CN) 2025-10-23 US disclosed
CN-119866332-A Iron death inhibitor-phenoxazine acetamides 维泰瑞隆(北京)生物科技有限公司 2025-04-22 CN disclosed
WO-2023245297-A1 FERROPTOSIS INHIBITORS AND USES THEREOF UNIVERSITY OF OTTAWA (CA) 2023-12-28 WO disclosed
CN-104136026-B Human glioma comprising MAO targetings/seeker part, which treats, uses compound 卫理公会医院研究所 2018-03-02 CN disclosed
CN-107556303-A A kind of compound, its synthetic method and utilize kit made of the compound and its application in glutathione detection 潍坊医学院 2018-01-09 CN disclosed
CN-107530062-A oral sampling swab and use thereof 宝洁公司 2018-01-02 CN disclosed
CN-106575078-A Photosensitive composition, method for producing cured film, touch panel display device, liquid crystal display device, and organic EL display device 富士胶片株式会社 2017-04-19 CN disclosed
CN-101970682-B Method for detecting and/or identifying clostridium difficile BIOMERIEUX SA 2015-05-13 CN disclosed
CN-101393361-B Liquid crystal device FUJI PHOTO FILM CO LTD 2012-03-28 CN disclosed
CN-101970682-A Method for detecting and/or identifying clostridium difficile BIOMERIEUX SA 2011-02-09 CN disclosed
CN-101548207-A Optical film and glass FUJIFILM CORP (JP) 2009-09-30 CN disclosed
CN-101534810-A Antiinflammatory agent comprising 2-aminophenol or derivative thereof as active ingredient HAYASHIBARA BIOCHEM LAB (JP) 2009-09-16 CN disclosed
CN-101393361-A Liquid crystal device FUJIFILM CORP (JP) 2009-03-25 CN disclosed
CN-1321120-C Phenoxazones, preparing process and pharmaceutical uses thereof UNIV ZHONGSHAN (CN) 2007-06-13 CN disclosed
CN-1788005-A Novel phenoxazinone derivatives as enzyme substrates and use thereof as indicator in the detection of microorganisms with peptidase activity BIOMERIEUX SA (FR) 2006-06-14 CN disclosed
CN-1524859-A Phenoxazones, preparing process and pharmaceutical uses thereof 中山大学 2004-09-01 CN disclosed
CN-1284075-A Novel compounds having CGMP-PDE inhibitory effect MOCHIDA PHARM CO LTD (JP) 2001-02-14 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250326726-A1 FERROPTOSIS INHIBITORS-PHENOXAZINE ACETAMIDES AIFM2, GPX4, FECH ALOX5 90/4885HTR2B 2594/4885MEN1 2988/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.