Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | LPL | P06858 | 7/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31034752 | 1.00 | MRGPRX4 (0.41) | MRGPRX4ESR2LPLLIPGDGAT1 | |
| SCHEMBL17129528 | 0.91 | ESR2 (0.41) | MRGPRX4ESR2LPLLIPGDGAT1 | |
| SCHEMBL31034717 | 0.87 | EGFR (0.46) | MRGPRX4ESR2LPLLIPGDGAT1 | |
| SCHEMBL27345509 | 0.87 | EGFR (0.46) | MRGPRX4ESR2LPLLIPGDGAT1 | |
| SCHEMBL27345508 | 0.86 | HIF1A (0.42) | MRGPRX4ESR2LPLLIPGDGAT1 | |
| SCHEMBL24058035 | 0.85 | DGAT1 (0.51) | MRGPRX4LPLLIPGDGAT1EGFR | |
| SCHEMBL21054557 | 0.84 | DGAT1 (0.43) | LPLLIPGDGAT1EGFRFFAR1 | |
| SCHEMBL27345772 | 0.83 | LMNA (0.46) | LPLLIPGDGAT1EGFRROCK1 | |
| SCHEMBL20510673 | 0.77 | LPL (0.49) | MRGPRX4ESR2LPLLIPGDGAT1 | |
| SCHEMBL28624112 | 0.77 | LPL (0.42) | ESR2LPLLIPGEGFRROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133605-A1 | SUBSTITUTED 3,7-DIHYDRO-1 H-PURINE-2,6-DIONES AND USE THEREOF | INVIOS GMBH (AT) | 2024-06-27 | — | — | WO | disclosed |