Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | LPL | P06858 | 7/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24058035 | 0.88 | DGAT1 (0.51) | LPLLIPGMRGPRX4DGAT1EGFR | |
| SCHEMBL21054557 | 0.88 | DGAT1 (0.43) | HIF1ALPLLIPGDGAT1EGFR | |
| SCHEMBL17129528 | 0.86 | ESR2 (0.41) | LPLLIPGMRGPRX4DGAT1EGFR | |
| SCHEMBL31034752 | 0.86 | MRGPRX4 (0.41) | HIF1ALPLLIPGMRGPRX4DGAT1 | |
| SCHEMBL27345504 | 0.86 | MRGPRX4 (0.41) | HIF1ALPLLIPGMRGPRX4DGAT1 | |
| SCHEMBL27345772 | 0.86 | LMNA (0.46) | LPLLIPGDGAT1EGFRROCK1 | |
| SCHEMBL27345779 | 0.85 | EGFR (0.48) | HIF1ALPLLIPGMRGPRX4DGAT1 | |
| SCHEMBL27345774 | 0.84 | RXRA (0.41) | HIF1ALPLLIPGMRGPRX4DGAT1 | |
| SCHEMBL27345776 | 0.83 | HIF1A (0.39) | HIF1ALPLLIPGDGAT1EGFR | |
| SCHEMBL27345419 | 0.83 | HIF1A (0.39) | HIF1ALPLLIPGDGAT1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133605-A1 | SUBSTITUTED 3,7-DIHYDRO-1 H-PURINE-2,6-DIONES AND USE THEREOF | INVIOS GMBH (AT) | 2024-06-27 | — | — | WO | disclosed |