Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28058630 | 0.89 | LIPG (0.47) | ALDH1A1LMNATSHRLIPG | |
| SCHEMBL27703122 | 0.86 | POLB (0.42) | POLBALDH1A1TP53MAPTHDAC6 | |
| SCHEMBL28310687 | 0.80 | ALDH1A1 (0.42) | ALDH1A1LMNATSHRCYP3A4TP53 | |
| SCHEMBL16742379 | 0.80 | ALDH1A1 (0.48) | POLBALDH1A1LMNATSHRCYP3A4 | |
| Benzyl Alcohol SCHEMBL27736133 | 0.79 | LIPG (0.42) | ALDH1A1LMNAPLK1MAPTKDM4E | |
| SCHEMBL9702942 | 0.78 | MAPT (0.44) | POLBALDH1A1LMNAMAPTHDAC6 | |
| SCHEMBL8756694 | 0.78 | KDM4E (0.49) | ALDH1A1LMNATSHRMAPTHDAC6 | |
| SCHEMBL28839036 | 0.77 | THRB (0.55) | ALDH1A1LMNATSHRCYP3A4TP53 | |
| SCHEMBL15486326 | 0.75 | KDM4E (0.47) | ALDH1A1LMNATSHRMAPTHDAC6 | |
| SCHEMBL11672538 | 0.75 | LTA4H (0.46) | ALDH1A1LMNATSHRCYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1035381-C | Radicicol derivatives, their preparation and their anti-tumor activity | SANKYO CO (JP) | 1997-07-09 | — | — | CN | disclosed |
| CN-1059720-A | Radicicol derivatives, its preparation method and anti-tumor activity thereof | SANKYO CO (JP) | 1992-03-25 | — | — | CN | disclosed |