Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27348016 | 0.81 | OPRK1 (0.56) | — | |
| SCHEMBL6949217 | 0.79 | TAAR1 (0.42) | LTB4RLTB4R2BCHEALOX5 | |
| SCHEMBL715536 | 0.77 | CYP3A4 (0.56) | ACHECYP3A4LMNAPARP1ALDH1A1 | |
| SCHEMBL6951407 | 0.72 | HTT (0.44) | ALDH1A1ALOX5 | |
| SCHEMBL5746820 | 0.72 | MAOB (0.68) | CYP3A4MAOBCYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL26130465 | 0.72 | ALOX5 (0.40) | ALDH1A1BCHEALOX5 | |
| SCHEMBL21225979 | 0.72 | ALOX5 (0.57) | ACHECYP3A4LMNAPARP1ALOX5 | |
| SCHEMBL8495462 | 0.72 | CCR6 (0.38) | CYP2D6LMNACYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL1561685 | 0.72 | CYP3A4 (0.56) | ACHECYP3A4LMNACYP4F2CYP4A11 | |
| SCHEMBL11455101 | 0.71 | ALDH1A1 (0.41) | CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1045780-A | The preparation of new sulfonamide derivatives | BOEHRINGER MANNHEIM GMBH (DE) | 1990-10-03 | — | — | CN | disclosed |